Stitcher: A Surface Reconstruction Tool for Highly Gyrified Brains.

Autor: Mynssen H; Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-971, Brazil.; Laboratório de Biologia Teórica e Matemática Experimental (MetaBIO), Instituto de Física, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.; Rede Brasileira de Neurobiodiversidade, Instituto de Física, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil., Avelino-de-Souza K; Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-971, Brazil. kamilla_bio@ufrj.br.; Laboratório de Biologia Teórica e Matemática Experimental (MetaBIO), Instituto de Física, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil. kamilla_bio@ufrj.br.; Rede Brasileira de Neurobiodiversidade, Instituto de Física, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil. kamilla_bio@ufrj.br., Chaim K; Rede Brasileira de Neurobiodiversidade, Instituto de Física, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.; LIM44, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, 05403-010, Brazil., Ribeiro VL; Instituto Biopesca, Praia Grande, SP, 11700-570, Brazil., Patzke N; Rede Brasileira de Neurobiodiversidade, Instituto de Física, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil. Nina.patzke@health-and-medical-university.de.; Faculty of Medicine, IMBB, HMU Health and Medical University, Potsdam, 14471, Germany. Nina.patzke@health-and-medical-university.de.; Department of Biological Science, Faculty of Sciences, Hokkaido University, Sapporo, 060-0810, Japan. Nina.patzke@health-and-medical-university.de., Mota B; Laboratório de Biologia Teórica e Matemática Experimental (MetaBIO), Instituto de Física, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.; Rede Brasileira de Neurobiodiversidade, Instituto de Física, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.
Jazyk: angličtina
Zdroj: Neuroinformatics [Neuroinformatics] 2024 Oct 10. Date of Electronic Publication: 2024 Oct 10.
DOI: 10.1007/s12021-024-09678-2
Abstrakt: Brain reconstruction, specially of the cerebral cortex, is a challenging task and even more so when it comes to highly gyrified brained animals. Here, we present Stitcher, a novel tool capable of generating such surfaces utilizing MRI data and manual segmentation. Stitcher makes a triangulation between consecutive brain slice segmentations by recursively adding edges that minimize the total length and simultaneously avoid self-intersection. We applied this new method to build the cortical surfaces of two dolphins: Guiana dolphin (Sotalia guianensis), Franciscana dolphin (Pontoporia blainvillei); and one pinniped: Steller sea lion (Eumetopias jubatus). Specifically in the case of P. blainvillei, two reconstructions at two different resolutions were made. Additionally, we also performed reconstructions for sub and non-cortical structures of Guiana dolphin. All our cortical mesh results show remarkable resemblance with the real anatomy of the brains, except P. blainvillei with low-resolution data. Sub and non-cortical meshes were also properly reconstructed and the spatial positioning of structures was preserved with respect to S. guianensis cerebral cortex. In a comparative perspective between methods, Stitcher presents compatible results for volumetric measurements when contrasted with other anatomical standard tools. In this way, Stitcher seems to be a viable pipeline for new neuroanatomical analysis, enhancing visualization and descriptions of non-primates species, and broadening the scope of compared neuroanatomy.
(© 2024. The Author(s).)
Databáze: MEDLINE
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