Burden of disease attributable to high body mass index: an analysis of data from the Global Burden of Disease Study 2021.

Autor:	Zhou XD; Department of Cardiovascular Medicine, the Heart Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China., Chen QF; Medical Care Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China., Yang W; Department of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China., Zuluaga M; Departament of Surgery, Universidad del Valle, Cali, Valle del Cauca, Colombia, United States., Targher G; Department of Medicine, University of Verona, Verona, Italy.; Metabolic Diseases Research Unit, IRCCS Sacro Cuore-Don Calabria Hospital, Negrar di Valpolicella, Italy., Byrne CD; Southampton National Institute for Health and Care Research Biomedical Research Centre, University Hospital Southampton, and University of Southampton, Southampton General Hospital, Southampton, UK., Valenti L; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.; Precision Medicine, Biological Resource Center Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Luo F; Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, China., Katsouras CS; First Department of Cardiology, University Hospital of Ioannina and Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece., Thaher O; Department of Surgery, Marien Hospital Herne, University Hospitals of the Ruhr University of Bochum, Herne, NRW, Germany., Misra A; Fortis-CDOC Center of Excellence for Diabetes, Metabolic Diseases, and Endocrinology, National Diabetes Obesity and Cholesterol Foundation and Diabetes Foundation, New Delhi, India., Ataya K; Department of Bariatric Surgery, University of Montreal, Montreal, Quebec, Canada., Oviedo RJ; Nacogdoches Center for Metabolic & Weight Loss Surgery, Nacogdoches Medical Center, Nacogdoches, TX, United States., Pik-Shan Kong A; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong SAR, China., Alswat K; Liver Disease Research Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Lonardo A; Department of Internal Medicine, Ospedale Civile di Baggiovara (-2023), Azienda Ospedaliero-Universitaria di Modena, Modena, Italy., Wong YJ; Department of Gastroenterology & Hepatology, Changi General Hospital, Singapore.; Liver Unit, Division of Gastroenterology & Hepatology, University of Alberta, Edmonton, Canada., Abu-Abeid A; Division of Surgery, Tel Aviv Sourasky Medical Center affiliated to Tel Aviv University, Tel Aviv, Israel., Al Momani H; Weight Management Unit, Royal NMC Hospital, Khalifa City, Abu Dhabi, United Arab Emirates., Ali A; Metabolic and Bariatric, Fatima8h hospital, Tehran, Iran., Molina GA; Department of Surgery, USFQ (Universidad San Francisco), Quito, Pichincha, Ecuador., Szepietowski O; Department of Surgery, Ashford and St Peter's Hospital, Chertsey, Surrey, United Kingdom., Jumaev NA; Department Surgical Diseases, Tashkent Medical Academy, Tashkent, Almazar, Uzbekistan., Kızılkaya MC; Department of Metabolic and Bariatric Surgery, Acibadem Atakent University Hospital, Istanbul, Turkey., Viveiros O; Department of Metabolic and Bariatric Surgery, Hospital Lusiadas Amadora, Amadora, Lisbon, Portugal., Toro-Huamanchumo CJ; Universidad San Ignacio de Loyola, Lima, Peru.; OBEMET Center for Obesity and Metabolic Health, Lima, Peru.; Nutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Western Australia, Australia., Yen Kok KY; Pengiran Anak Puteri Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Bandar Seri Begawan, Brunei-Muara, Brunei., Ospanov O; Surgical Disease and Bariatric Surgery, Astana Medical University, Astana, Aqmola, Kazakhstan., Abbas SI; Department of Metabolic and Bariatric Surgery, Iranian Hospital Dubai, Dubai, United Arab Emirates., Robertson AG; Department of Upper Gastrointestinal Surgery, Royal Infirmary Edinburgh, Edinburgh, United Kingdom., Fouad Y; Department of Gastroenterology, Hepatology and Endemic Medicine, Faculty of Medicine, Minia University, Minia, Egypt., Mantzoros CS; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.; Section of Endocrinology, Boston VA Healthcare System, Harvard Medical School, Boston, MA, USA., Zhang H; Department of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, China., Méndez-Sánchez N; Liver Research Unit, Medica Sur Clinic & Foundation, Mexico City, Mexico., Sookoian S; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.; Faculty of Health Science, Maimónides University, Buenos Aires, Argentina.; Clinical and Molecular Hepatology, Translational Health Research Center (CENITRES), Maimónides University, Buenos Aires, Argentina., Chan WK; Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Treeprasertsuk S; Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Adams L; Department of Hepatology, Sir Charles Gairdner Hospital, Perth, Australia.; Medical School, The University of Western Australia, Perth, Australia., Ocama P; Department of Medicine, Makerere University of College of Health Sciences, Kampala, Uganda., Ryan JD; Department of Hepatology, RCSI School of Medicine and Medical Sciences, Dublin/Beaumont Hospital, Dublin, Ireland., Perera N; Department of Medicine, University of Sri Jayewardenepura, Nugegoda, Sri Lanka., Sharara AI; Division of Gastroenterology and Hepatology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon., Al-Busafi SA; Department of Medicine, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman., Opio CK; Department of Medicine, Aga Khan University, Nairobi, Kenya., Garcia M; Departament of Metabolic and Bariatric Surgery, Tu Opcion Bariatrica/Swiss Hospital, Monterrey, Mexico., Lim-Loo MC; Department of Surgery, Chinese General Hospital and Medical Center, Manila, Philippines., Ruiz-Úcar E; Department of Metabolic, Bariatric and Endocrine Surgery, Fuenlabrada University Hospital, Madrid, Spain., Prasad A; Surgical Gastroenterology, Bariatric and Robotic Surgery, Indraprastha Apollo Hospital, New Delhi, India., Casajoana A; Departament of Esophagogastric and Bariatric Surgery, Hospital del Mar de Barcelona, Barcelona, Spain., Abdelbaki TN; Department of General Surgery, Alexandria University Faculty of Medicine, Alexandria, Egypt., Zheng MH; MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China.
Jazyk:	angličtina
Zdroj:	EClinicalMedicine [EClinicalMedicine] 2024 Sep 24; Vol. 76, pp. 102848. Date of Electronic Publication: 2024 Sep 24 (Print Publication: 2024).
DOI:	10.1016/j.eclinm.2024.102848
Abstrakt:	Background: Obesity represents a major global health challenge with important clinical implications. Despite its recognized importance, the global disease burden attributable to high body mass index (BMI) remains less well understood. Methods: We systematically analyzed global deaths and disability-adjusted life years (DALYs) attributable to high BMI using the methodology and analytical approaches of the Global Burden of Disease Study (GBD) 2021. High BMI was defined as a BMI over 25 kg/m 2 for individuals aged ≥20 years. The Socio-Demographic Index (SDI) was used as a composite measure to assess the level of socio-economic development across different regions. Subgroup analyses considered age, sex, year, geographical location, and SDI. Findings: From 1990 to 2021, the global deaths and DALYs attributable to high BMI increased more than 2.5-fold for females and males. However, the age-standardized death rates remained stable for females and increased by 15.0% for males. Similarly, the age-standardized DALY rates increased by 21.7% for females and 31.2% for males. In 2021, the six leading causes of high BMI-attributable DALYs were diabetes mellitus, ischemic heart disease, hypertensive heart disease, chronic kidney disease, low back pain and stroke. From 1990 to 2021, low-middle SDI countries exhibited the highest annual percentage changes in age-standardized DALY rates, whereas high SDI countries showed the lowest. Interpretation: The worldwide health burden attributable to high BMI has grown significantly between 1990 and 2021. The increasing global rates of high BMI and the associated disease burden highlight the urgent need for regular surveillance and monitoring of BMI. Funding: National Natural Science Foundation of China and National Key R&D Program of China. Competing Interests: Christopher D. Byrne has received grant support from Echosens. Ming-Hua Zheng has received honoraria for lectures from AstraZeneca, Hisky Medical Technologies and Novo Nordisk, consulting fees from Boehringer Ingelheim. Anoop Misra has received honoraria from Novo Nordisk, AstraZendeca, Janssen, and Boehringer Ingelheim. Wah-Kheong Chan is a consultant or advisory board member for Abbott, Roche, Abbvie, Boehringer Ingelheim and Novo Nordisk; and a speaker for Abbott, Novo Nordisk, Echosens, Viatris and Hisky Medical. No other disclosures were reported; John D. Ryan received consultancy fees from Falk, Gilead, Pfizer and a speaker honorarium from Takeda. Christos S. Mantzoros reports grants through his institution from Merck, Massachusetts Life Sciences Center and Boehringer Ingelheim, has received grants through his Institution and personal consulting fees from Coherus Inc. and AltrixBio, he reports personal consulting fees and support with research reagents from Ansh Inc., collaborative research support from LabCorp Inc., reports personal consulting fees from Olympus, Genfit, Lumos, Novo Nordisk, Amgen, Biodexa, Laekna, Corcept, Intercept, 89 Bio, Madrigal, Aligos, Esperion and Regeneron, travel support and fees from UptoDate, TMIOA, Elsevier, and the Cardio Metabolic Health Conference. The other authors report no disclosure. (© 2024 The Author(s).)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu