Socioeconomic factors and COVID-19 mortality in immune-mediated rheumatic diseases patients: regional analysis from Argentina, Mexico and Brazil.

Autor: Martinez-Martinez MU; Hospital General de Subzona No. 9, Instituto Mexicano del Seguro Social, San Luis, Potosí, México., Isnardi CA; Research Unit, Argentine Society of Rheumatology, CABA, Argentina., Alpizar-Rodriguez D; Research Unit, Colegio Mexicano de Reumatología, Mexico City, Mexico., Pons-Estel GJ; Research Unit, Argentine Society of Rheumatology, CABA, Argentina., Virasoro BM; Research Unit, Argentine Society of Rheumatology, CABA, Argentina., Alfaro MA; Research Unit, Argentine Society of Rheumatology, CABA, Argentina., Petkovic I; Investigator of the SAR-COVID Registry, Argentine Society of Rheumatology, CABA, Argentina.; Sanatorio Petkovic, Tunuyán, Mendoza, Argentina., Quintana R; Investigator of the SAR-COVID Registry, Argentine Society of Rheumatology, CABA, Argentina.; 6Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR), Rosario, Santa Fe, Argentina., Berbotto G; Investigator of the SAR-COVID Registry, Argentine Society of Rheumatology, CABA, Argentina.; Sanatorio Británico Rosario, Chief of the Rheumatology Service, Rosario, Santa Fe, Argentina., Salinas MJH; Investigator of the SAR-COVID Registry, Argentine Society of Rheumatology, CABA, Argentina.; Reumatologa CEMMA, Universidad Nacional de La Rioja, La Rioja, Argentina., Ornella S; Investigator of the SAR-COVID Registry, Argentine Society of Rheumatology, CABA, Argentina.; HIGA San Martin, La Plata, Buenos Aires, Argentina., Pera M; Investigator of the SAR-COVID Registry, Argentine Society of Rheumatology, CABA, Argentina.; Hospital Angel C Padilla, San Miguel de Tucuman, Tucuman, Argentina., Colunga-Pedraza IJ; Investigator of CMR-COVID Registry, Mexican College of Rheumatology, Mexico City, Mexico.; Hospital Universitario José Eleuterio González, Monterrey, Mexico., Irazoque-Palazuelos F; Investigator of CMR-COVID Registry, Mexican College of Rheumatology, Mexico City, Mexico.; Centro de Investigación y Tratamiento Reumatológico S.C., Rheumatology, Mexico City, Mexico., Reyes-Cordero G; Investigator of CMR-COVID Registry, Mexican College of Rheumatology, Mexico City, Mexico.; Facultad de Medicina y Ciencias Biomédicas, Universidad Autónoma de Chihuahua, Chihuahua, Private Practice Rheumatology, Chihuahua, Mexico., Rodriguez-Reyna TS; Investigator of CMR-COVID Registry, Mexican College of Rheumatology, Mexico City, Mexico.; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Veloz-Aranda JA; Investigator of CMR-COVID Registry, Mexican College of Rheumatology, Mexico City, Mexico.; Hospital Regional ISSSTE, Leon, Mexico., Skinner-Taylor CM; Investigator of CMR-COVID Registry, Mexican College of Rheumatology, Mexico City, Mexico.; Hospital Universitario José Eleuterio González, Monterrey, Mexico., Juárez-Mora IM; Investigator of CMR-COVID Registry, Mexican College of Rheumatology, Mexico City, Mexico.; Instituto Mexicano del Seguro Social, Internal Medicine, Mexico City, Mexico., Silveira LH; Investigator of CMR-COVID Registry, Mexican College of Rheumatology, Mexico City, Mexico.; Instituto Nacional de Cardiología, Mexico City, Mexico., Marques CDL; ReumaCoV-Brasil, Brazilian Society of Rheumatology, São Paulo, Brazil.; Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil., Xavier RM; ReumaCoV-Brasil, Brazilian Society of Rheumatology, São Paulo, Brazil.; Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil., Kakehasi AM; ReumaCoV-Brasil, Brazilian Society of Rheumatology, São Paulo, Brazil.; Universidade Federal de Minas Gerais, Alfredo Balena Avenue, 190, Belo Horizonte, Minas Gerais, CEP: 30130-100, Brazil., Gomides AP; ReumaCoV-Brasil, Brazilian Society of Rheumatology, São Paulo, Brazil.; UniCEUB, Brasília, Distrito Federal, Brazil., Dos Reis-Neto ET; ReumaCoV-Brasil, Brazilian Society of Rheumatology, São Paulo, Brazil.; Universidade Federal de São Paulo, São Paulo, São Paulo, Brazil., Pileggi GS; ReumaCoV-Brasil, Brazilian Society of Rheumatology, São Paulo, Brazil.; Universidade Federal de São Paulo, São Paulo, São Paulo, Brazil., Ferreira GA; ReumaCoV-Brasil, Brazilian Society of Rheumatology, São Paulo, Brazil.; Universidade Federal de Minas Gerais, Alfredo Balena Avenue, 190, Belo Horizonte, Minas Gerais, CEP: 30130-100, Brazil., da Mota LMH; ReumaCoV-Brasil, Brazilian Society of Rheumatology, São Paulo, Brazil.; Medical Sciences, Medical School, Universidade de Brasília, Brasília, Distrito Federal, Brazil., Pinheiro MM; ReumaCoV-Brasil, Brazilian Society of Rheumatology, São Paulo, Brazil.; Universidade Federal de São Paulo, São Paulo, São Paulo, Brazil., Calderaro DC; ReumaCoV-Brasil, Brazilian Society of Rheumatology, São Paulo, Brazil. dccalderaro@gmail.com.; Universidade Federal de Minas Gerais, Alfredo Balena Avenue, 190, Belo Horizonte, Minas Gerais, CEP: 30130-100, Brazil. dccalderaro@gmail.com.
Jazyk: angličtina
Zdroj: Advances in rheumatology (London, England) [Adv Rheumatol] 2024 Oct 09; Vol. 64 (1), pp. 78. Date of Electronic Publication: 2024 Oct 09.
DOI: 10.1186/s42358-024-00418-3
Abstrakt: Background: SARS-CoV-2 infection has become a major international issue, not only from a medical point of view, but also social, economic and political. Most of the available information comes from the United States, Europe, and China, where the population and the socioeconomic status are very different from Latin American countries. This study evaluates the effect of regional socioeconomic characteristics on mortality due SARS-CoV-2 infection in patients with immune-mediated rheumatic diseases (IMRD) from Argentina, Mexico and Brazil.
Methods: Data from three national registries, SAR-COVID (Argentina), CMR-COVID (Mexico) and ReumaCoV-Brasil (Brazil), were combined. Adult IMRD patients with SARS-CoV-2 infection were recruited. National data for each province/state, including population density, number of physicians per inhabitant, income, unemployment, GINI index, Municipal Human Development Index (MHDI), stringency index, vaccination rate and most frequent viral strains per period were assessed as risk factors for mortality due to COVID-19.
Results: A total of 4744 patients were included, 2534 (53.4%) from SAR-COVID, 1166 (24.6%) from CMRCOVID and 1044 (22.0%) from ReumaCoV-Brasil. Mortality due to COVID-19 was 5.4%. In the multivariable analysis, higher number of physicians per 1000 inhabitants and being infected during the vaccination period of each country were associated with lower mortality. After adjustment for socioeconomic factors, there was no association with country of residence and mortality.
Conclusion: These findings corroborate the complex interplay between socioeconomic factors, rheumatic disease activity, and regional disparities as determinants of death due to COVID-19 in Argentina, Brazil and Mexico. Thus, this research provides valuable insights for guiding public health policies and clinical practice in the ongoing fight against the COVID-19 pandemic.
(© 2024. The Author(s).)
Databáze: MEDLINE
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