Tertiary lymphoid structure formation: A matter of tumor-immune co-evolution.
| Autor: | van der Leun AM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA; Broad Institute of MIT and Harvard, Cambridge, USA; Departments of Cell Biology and Pathology, Harvard Medical School, Boston, USA. Electronic address: anne_vanderleun@dfci.harvard.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Molecular immunology [Mol Immunol] 2024 Nov; Vol. 175, pp. 143-145. Date of Electronic Publication: 2024 Oct 09. |
| DOI: | 10.1016/j.molimm.2024.09.012 |
| Abstrakt: | The immune make-up of human tumors is dynamic over the course of cancer progression. However, what factors drive spatiotemporal changes in the tumor-immune landscape is not well-known. In issue 3 of Cell Reports Medicine, Liu, You, Lan and Ren et al. demonstrate that the development of tertiary lymphoid structures (TLSs) is a stepwise process that co-occurs with tumor progression in patients with lung adenocarcinoma (LUAD). (Copyright © 2024 Elsevier Ltd. All rights reserved.) |
| Databáze: | MEDLINE |
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