An uncommon combination: a case report of herpes simplex virus encephalitis induced takotsubo cardiomyopathy.

Autor:	London J; Department of Internal Medicine, Long Island Community Hospital, Patchogue, NY, USA., Tisheh L; Department of Internal Medicine, Long Island Community Hospital, Patchogue, NY, USA., Lim MB; Department of Internal Medicine, Long Island Community Hospital, Patchogue, NY, USA., Bulancea S; Department of Internal Medicine, Long Island Community Hospital, Patchogue, NY, USA., Kharchenko I; Department of Internal Medicine, Long Island Community Hospital, Patchogue, NY, USA., Pratap B; Department of Cardiology, Long Island Community Hospital, Patchogue, NY, USA., Tharayil Z; Department of Internal Medicine, Long Island Community Hospital, Patchogue, NY, USA., Gupta R; Department of Internal Medicine, Long Island Community Hospital, Patchogue, NY, USA.
Jazyk:	angličtina
Zdroj:	AME case reports [AME Case Rep] 2024 Aug 02; Vol. 8, pp. 95. Date of Electronic Publication: 2024 Aug 02 (Print Publication: 2024).
DOI:	10.21037/acr-24-53
Abstrakt:	Background: Takotsubo cardiomyopathy, also known as stress-induced cardiomyopathy or broken-heart syndrome, is a non-ischemic cardiomyopathy that presents as a transient regional systolic dysfunction of the left ventricle with minimal increase in troponins. The pathogenesis of takotsubo cardiomyopathy is not well understood. Some possible theories include increased catecholamines causing sympathetic overdrive, microvascular dysfunction, coronary spasm, or inflammation. The association of herpes simplex virus (HSV) encephalitis with takotsubo cardiomyopathy has rarely been reported with only two cases being described in literature. Case Description: We present a patient that came in with altered mental status who was found to have herpes simplex virus 1 (HSV-1) encephalitis. During his hospital stay, the patient had developed shortness of breath on hospital day 3. The patient's troponin was found to be mildly elevated and echocardiogram revealed takotsubo cardiomyopathy with left ventricle ejection fraction (LVEF) of 20% and severe hypokinesis of all left ventricle segments except the basal segments. His echocardiogram nine months prior revealed a LVEF 60-65%. He was treated with intravenous (IV) acyclovir and repeat echocardiogram three weeks following hospitalization revealed resolution of his takotsubo cardiomyopathy. Conclusions: Physicians should keep HSV encephalitis induced takotsubo cardiomyopathy in their differential diagnosis when patients present with HSV encephalitis along with shortness of breath and pulmonary vascular congestion on imaging. Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://acr.amegroups.com/article/view/10.21037/acr-24-53/coif). The authors have no conflicts of interest to declare. (2024 AME Publishing Company. All rights reserved.)
Databáze:	MEDLINE
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