Comprehensive Insights into Microbial Lipases: Unveiling Structural Dynamics, Catalytic Mechanism, and Versatile Applications.

Autor: Shah H; Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing, 100048, People's Republic of China.; Key Laboratory of Brewing Microbiome and Enzymatic Molecular Engineering, China General Chamber of Commerce, Beijing Technology and Business University (BTBU), Haidian District, No. 11 Fucheng Street, Beijing, 100048, People's Republic of China.; School of Food and Health, Beijing Technology and Business University (BTBU), Beijing, 100048, People's Republic of China., Zhang C; Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing, 100048, People's Republic of China.; China Bio-Specialty Food Enzyme Technology Research Development and Promotion Center, Beijing, 100048, People's Republic of China.; Key Laboratory of Brewing Microbiome and Enzymatic Molecular Engineering, China General Chamber of Commerce, Beijing Technology and Business University (BTBU), Haidian District, No. 11 Fucheng Street, Beijing, 100048, People's Republic of China., Khan S; College of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310014, China., Patil PJ; Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing, 100048, People's Republic of China.; Key Laboratory of Brewing Microbiome and Enzymatic Molecular Engineering, China General Chamber of Commerce, Beijing Technology and Business University (BTBU), Haidian District, No. 11 Fucheng Street, Beijing, 100048, People's Republic of China.; School of Food and Health, Beijing Technology and Business University (BTBU), Beijing, 100048, People's Republic of China., Li W; Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing, 100048, People's Republic of China.; Key Laboratory of Brewing Microbiome and Enzymatic Molecular Engineering, China General Chamber of Commerce, Beijing Technology and Business University (BTBU), Haidian District, No. 11 Fucheng Street, Beijing, 100048, People's Republic of China.; School of Food and Health, Beijing Technology and Business University (BTBU), Beijing, 100048, People's Republic of China., Xu Y; Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing, 100048, People's Republic of China.; Key Laboratory of Brewing Microbiome and Enzymatic Molecular Engineering, China General Chamber of Commerce, Beijing Technology and Business University (BTBU), Haidian District, No. 11 Fucheng Street, Beijing, 100048, People's Republic of China.; School of Food and Health, Beijing Technology and Business University (BTBU), Beijing, 100048, People's Republic of China., Ali A; Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing, 100048, People's Republic of China.; Key Laboratory of Brewing Microbiome and Enzymatic Molecular Engineering, China General Chamber of Commerce, Beijing Technology and Business University (BTBU), Haidian District, No. 11 Fucheng Street, Beijing, 100048, People's Republic of China.; School of Food and Health, Beijing Technology and Business University (BTBU), Beijing, 100048, People's Republic of China., Liang E; Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing, 100048, People's Republic of China.; Key Laboratory of Brewing Microbiome and Enzymatic Molecular Engineering, China General Chamber of Commerce, Beijing Technology and Business University (BTBU), Haidian District, No. 11 Fucheng Street, Beijing, 100048, People's Republic of China.; School of Food and Health, Beijing Technology and Business University (BTBU), Beijing, 100048, People's Republic of China., Li X; Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing, 100048, People's Republic of China. lixt@btbu.edu.cn.; China Bio-Specialty Food Enzyme Technology Research Development and Promotion Center, Beijing, 100048, People's Republic of China. lixt@btbu.edu.cn.; Key Laboratory of Brewing Microbiome and Enzymatic Molecular Engineering, China General Chamber of Commerce, Beijing Technology and Business University (BTBU), Haidian District, No. 11 Fucheng Street, Beijing, 100048, People's Republic of China. lixt@btbu.edu.cn.; School of Food and Health, Beijing Technology and Business University (BTBU), Beijing, 100048, People's Republic of China. lixt@btbu.edu.cn.
Jazyk: angličtina
Zdroj: Current microbiology [Curr Microbiol] 2024 Oct 07; Vol. 81 (11), pp. 394. Date of Electronic Publication: 2024 Oct 07.
DOI: 10.1007/s00284-024-03904-5
Abstrakt: Microbial lipases (MLs) are pivotal biocatalysts in lipid biotechnology due to their diverse enzymatic properties and substrate specificity, garnering significant research attention. This comprehensive review explores the significance of MLs in biocatalysis, providing insights into their structure, catalytic domain, and oxyanion hole. The catalytic mechanism is elucidated, highlighting the molecular processes driving their efficiency. The review delves into ML sources, spanning fungi, yeasts, bacteria, and actinomycetes, followed by a discussion on classification and characterization. Emphasizing the scattered findings in the literature, the paper consolidates the latest information on ML applications across various industries, from food and pharmaceuticals to biofuel production and the paper and pulp industry. The review captures the dynamic landscape of ML research, emphasizing their structure-function relationships and practical implications across diverse sectors.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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