Rubella seroprevalence among unvaccinated school-aged children in Jos, North Central, Nigeria.

Autor:	Waziri HS; African Field Epidemiology Network, Abuja, Nigeria., Giwa F; Ahmadu Bello University Zaria, Kaduna State, Nigeria., Olayinka AT; Ahmadu Bello University Zaria, Kaduna State, Nigeria., Waziri NE; African Field Epidemiology Network, Abuja, Nigeria., Da'am CK; Africa Centres for Disease Control and Prevention, Jabi, Abuja, Nigeria., Mohammed Y; African Field Epidemiology Network, Abuja, Nigeria., Nguku P; African Field Epidemiology Network, Abuja, Nigeria., Dahal SA; Department of Medical Microbiology, Jos University Teaching Hospital, Plateau State, Nigeria., Nwokoro U; Department of Community Medicine, University of Nigeria Teaching Hospital, Enugu State, Nigeria., Nakah J; Department of Medical Microbiology, Jos University Teaching Hospital, Plateau State, Nigeria., Maktep YD; Department of Medical Microbiology, Jos University Teaching Hospital, Plateau State, Nigeria., Olowo-Okere A; Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, University of Abuja, Abuja, Nigeria.
Jazyk:	angličtina
Zdroj:	The Pan African medical journal [Pan Afr Med J] 2024 Sep 02; Vol. 49, pp. 1. Date of Electronic Publication: 2024 Sep 02 (Print Publication: 2024).
DOI:	10.11604/pamj.2024.49.1.44172
Abstrakt:	Introduction: rubella poses a significant public health threat, particularly in developing countries, where congenital rubella remains a preventable concern. This cross-sectional study examined rubella seroprevalence among children aged 10 and under from May to September 2016 in Jos, Nigeria. Methods: using a multistage sampling method, eligible participants who had not been vaccinated against the rubella virus and consented to participate in the study were recruited across schools in the city. Rubella-specific IgG and IgM antibodies were detected from eluted serum collected from the participants using the enzyme-linked immunosorbent assay (ELISA). Data analysis and visualization was done using the R software version 4.3.1. Results: of the 405 participants investigated in this study, 336 (82.96%) tested positive for rubella IgG, while 9 (2.22%) tested positive for rubella IgM. Factors such as age ≥ 5 years and lack of Western education showed significant associations with rubella seropositivity. Conclusion: this study highlights the seroprevalence of rubella IgG and IgM antibodies among children aged 10 and under in Jos, Nigeria. The significant associations between rubella seropositivity and factors such as age ≥ 5 years and lack of Western education underscore the necessity for an effective rubella vaccination program to prevent congenital rubella syndrome (CRS). Competing Interests: The authors declare no competing interests. (Copyright: Hyelshilni Samuel Waziri et al.)
Databáze:	MEDLINE
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