Chlorophyll-Induced Lamellar to Nonlamellar Phase Transitions and Dynamical Heterogeneity in Plant Thylakoid Membranes.
| Autor: | Sahu S; Department of Chemistry, IIT Jodhpur, Jodhpur, Rajasthan 342037, India., Saini R; Department of Chemistry, IIT Jodhpur, Jodhpur, Rajasthan 342037, India., Debnath A; Department of Chemistry, IIT Jodhpur, Jodhpur, Rajasthan 342037, India. |
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| Jazyk: | angličtina |
| Zdroj: | The journal of physical chemistry. B [J Phys Chem B] 2024 Oct 17; Vol. 128 (41), pp. 10154-10164. Date of Electronic Publication: 2024 Oct 07. |
| DOI: | 10.1021/acs.jpcb.4c04164 |
| Abstrakt: | Chlorophyll a (CLA) pigments and thylakoid membranes are crucial components of plants for photosynthesis. To understand the effect of CLA on the structure and dynamics of thylakoid membranes, coarse-grained molecular dynamics (CG MD) simulations of thylakoid membranes are performed by varying the numbers of CLA at 293 K using MARTINI-2 force fields. The membrane undergoes a lamellar to nonlamellar phase transition above a critical concentration of CLA. The CLAs dynamically form aggregates of different orders and preferentially fetch the least unsaturated nonbilayer-forming lipids around them, resulting in a nonlamellar phase with fused regions. These fused regions cause a structural arrest of CLA and lipids, inducing dynamic heterogeneity manifested by non-Gaussian parameters and van Hove correlation functions. The lamellar to nonlamellar phase transition of the membrane is associated with a drastic reduction in correlation length of the immobile CLA and lipids governed by the fused topology. Such insights into CLA-induced structural transitions in thylakoid membranes are pertinent for understanding nonphotochemical quenching mechanisms and hold promise for designing future artificial photosynthetic materials and applications in photodynamic therapy. |
| Databáze: | MEDLINE |
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