Bringing PERT to Pediatrics: Initial Experience and Outcomes of a Pediatric Multidisciplinary Pulmonary Embolism Response Team (PERT).

Autor:	Dang MP; University of Texas Southwestern Medical Center, TX; Department of Pediatric; Division of Hematology/Oncology; Children's Health System of Texas, TX., Cheng A; University of Texas Southwestern Medical Center, TX; Department of Pediatric., Garcia J; University of Texas Southwestern Medical Center, TX; Department of Pediatric; Division of Hematology/Oncology; Children's Health System of Texas, TX., Lee Y; Division of Hematology/Oncology; Children's Health System of Texas, TX., Parikh M; University of Texas Southwestern Medical Center, TX; Department of Anesthesia., McMichael ABV; Phoenix Children's Hospital, Department of Child Health, University of Arizona College of Medicine, Phoenix, AZ., Han BL; University of Texas Southwestern Medical Center, TX; Department of Radiology; Division of Pediatric Radiology., Pimpalwar S; University of Texas Southwestern Medical Center, TX; Department of Radiology; Division of Pediatric Radiology., Rinzler ES; University of Texas Southwestern Medical Center, TX; Department of Radiology; Division of Pediatric Radiology., Hoffman OL; University of Texas Southwestern Medical Center, TX; Department of Pediatric; Children's Health System of Texas, TX; Division of Critical Care., Baltagi SA; University of Texas Southwestern Medical Center, TX; Department of Pediatric; Children's Health System of Texas, TX; Division of Critical Care., Bowens C; University of Texas Southwestern Medical Center, TX; Department of Pediatric; Children's Health System of Texas, TX; Division of Critical Care., Divekar AA; University of Texas Southwestern Medical Center, TX; Department of Pediatric; Children's Health System of Texas, TX; Division of Pediatric Cardiology., Davis Volk P; University of Texas Southwestern Medical Center, TX; Department of Pediatric; Children's Health System of Texas, TX; Division of Critical Care., Huang CJ; University of Texas Southwestern Medical Center, TX; Department of Pediatric; Children's Health System of Texas, TX; Division of Pediatric Emergency Medicine., Veeram Reddy SR; University of Texas Southwestern Medical Center, TX; Department of Pediatric; Children's Health System of Texas, TX; Division of Pediatric Cardiology., Arar Y; University of Texas Southwestern Medical Center, TX; Children's Health System of Texas, TX; Division of Pediatric Cardiology., Zia A; University of Texas Southwestern Medical Center, TX; Department of Pediatric; Division of Hematology/Oncology; Children's Health System of Texas, TX. Electronic address: Ayesha.zia@utsouthwestern.edu.
Jazyk:	angličtina
Zdroj:	Chest [Chest] 2024 Oct 03. Date of Electronic Publication: 2024 Oct 03.
DOI:	10.1016/j.chest.2024.09.028
Abstrakt:	Background: Multidisciplinary pulmonary embolism response teams (PERTs) streamline care of adults with life-threatening pulmonary embolism (PE). Given rarity of pediatric PE, developing a clinical, educational, and research PERT paradigm is a novel and underused concept in pediatrics. Research Question: Is a PERT feasible in pediatrics, and does it improve PE care? Study Design and Methods: A strategy-to-execution proposal to launch a pediatric PERT was developed for institutional buy-in. Key stakeholders collectively implemented the PERT. Data were collected for the 2-year pre-PERT and post-PERT eras, and outcomes were compared. Results: PERT implementation took 12 months. Our PERT, led by hematology, is composed of pediatric experts in emergency medicine, critical care, interventional cardiology, anesthesiology, and interventional radiology. Data on 30 patients pre-PERT and 31 patients post-PERT were analyzed. Pre-PERT, 10% (3 of 30), 13% (4 of 30), 20% (6 of 30), and 57% (17 of 30), and post-PERT, 3% (1 of 31), 10% (3 of 31), 16% (5 of 31), and 71% (22 of 31) were categorized as high-risk, intermediate-low-risk, intermediate-high-risk, and low-risk PE, respectively. Post-PERT, there were 13 unique PERT activations. PERT was activated on all eligible patients with PE and, additionally, on 4 low-risk PEs. Time to echocardiogram was shorter post-PERT (4.7 vs 2 hours, P = .0147). Anticoagulation was ordered (90 vs 54 minutes, P = .003) and given sooner (154 vs 113 minutes, P = .049) post-PERT. There were no differences in time to reperfusion therapies (12 hours pre-PERT vs 8.7 hours post-PERT, P = .10). Five of 6 (83.3%) eligible (intermediate-high and high-risk) patients received reperfusion therapies in the post-PERT era compared to 3 of 8 (37.5%) eligible patients in the pre-PERT era (P = .0001). There were no differences in major bleeding, mortality, or length of stay in either era. Interpretation: The pediatric PERT paradigm was successfully created and adopted locally. Our PERT enhanced access to experts, facilitated timely advanced therapies, and held value for low-risk PE. The University of Texas Southwestern Medical Center and Children's Health System of Texas pediatric PERT may serve as a best practice model for streamlining care for pediatric PE. Competing Interests: Financial/Nonfinancial Disclosures None declared. (Copyright © 2024 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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