"Cancer Integrin" α v β 6 Imaging With 68 Ga-Trivehexin PET/CT in Assessment of Ovarian Carcinoma.
| Autor: | Singh P; From the Department of Nuclear Medicine, All India Institute of Medical Sciences, Bhubaneswar, India., Agrawal K, Emerson R, Baranwal A, Patro PSS, Parida GK |
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| Jazyk: | angličtina |
| Zdroj: | Clinical nuclear medicine [Clin Nucl Med] 2024 Nov 01; Vol. 49 (11), pp. e619-e621. Date of Electronic Publication: 2024 Oct 03. |
| DOI: | 10.1097/RLU.0000000000005485 |
| Abstrakt: | Abstract: Peritoneal cancer index is an integral parameter for preoperative assessment of peritoneal disease. Current imaging modalities including 18 F-FDG PET/CT, though superior to CT, underestimate the disease extent, mainly due to its high physiological background activity. Novel "cancer integrin" targeting imaging with 68 Ga-trivehexin demonstrates limited physiological activity in the abdomen with superior target-to-background ratio than 18 F-FDG PET/CT. Thus, we describe the first case demonstrating potential utility of novel "cancer integrin" αvβ6 imaging agent 68 Ga-trivehexin for assessment of disease burden in advanced epithelial ovarian cancer. Competing Interests: Conflicts of interest and sources of funding: none declared. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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