Cryobiopsy as a Diagnostic Tool in Lung Transplantation: A Case Report.
| Autor: | Garcia Rueda JE; Internal Medicine, Pontifical Bolivarian University, Medellín, COL., Botero Bahamón JD; Pulmonology, Cardio Clinical VID, Medellín, COL., Cardona Palacio A; Pathology, Pablo Tobón Uribe Hospital, Medellín, COL., Campo Campo FJ; Pulmonology, Cardio Clinical VID, Medellín, COL., Palacio Mejía MI; Epidemiology, Cardio Clinical VID, Medellín, COL. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Sep 03; Vol. 16 (9), pp. e68554. Date of Electronic Publication: 2024 Sep 03 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.68554 |
| Abstrakt: | Lung transplantation is an option for patients with advanced lung pathologies. Transbronchial biopsies are routinely conducted during the first year to manage acute rejection episodes, with chronic rejection, particularly bronchiolitis obliterans syndrome, becoming a significant concern thereafter. A 34-year-old patient with a diagnosis of primary ciliary dyskinesia was admitted to the emergency room due to a severe exacerbation that caused mixed respiratory failure. He required intubation and extracorporeal membrane oxygenation (ECMO) support as a bridge to bilateral lung transplantation. Post-transplantation, cryobiopsy was implemented according to local protocol, revealing A3 rejection without microbiological isolations. The implementation of cryobiopsy in lung transplantation proves to be an effective diagnostic strategy, offering enhanced tissue evaluation and improved diagnostic performance in both acute and chronic cellular rejection. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Garcia Rueda et al.) |
| Databáze: | MEDLINE |
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