Clinical and Coronary Angiographic Insights Into Acute ST-Elevation Myocardial Infarction in Young Patients: A Study From a Tertiary Care Cardiac ICU.

Autor:	Ramanathan N; Internal Medicine, Jagadguru Sri Shivarathreeshwara (JSS) Academy of Higher Education and Research, Mysore, IND., Babu HM; Internal Medicine, Jagadguru Sri Shivarathreeshwara (JSS) Academy of Higher Education and Research, Mysore, IND., Nair A; Internal Medicine, Altnagelvin Hospital, Londonderry, GBR., Mohan D; Internal Medicine, Aarupadai Veedu Medical College & Hospital, Pondicherry, IND., Rob MA; Critical Care, East Lancashire Hospitals NHS Trust, Blackburn, GBR., Dey RK; Orthopedics, University Hospitals Sussex NHS Foundation Trust, Brighton and Hove, GBR., Jain R; Critical Care, Cumberland Infirmary, North Cumbria Integrated Care NHS Foundation Trust, Carlisle, GBR., Nallathambi N; Internal Medicine, Madras Medical College, Chennai, IND., Muthiah A; Internal Medicine, Tirunelveli Medical College, Tirunelveli, IND., Lohakare T; Child Health Nursing, Shrimati Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Higher Education & Research, Wardha, IND., Rathi T; Medicine, Mahatma Gandhi Institute of Medical Sciences, Wardha, IND.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Sep 02; Vol. 16 (9), pp. e68484. Date of Electronic Publication: 2024 Sep 02 (Print Publication: 2024).
DOI:	10.7759/cureus.68484
Abstrakt:	Background This investigation addresses the major effects of early-onset coronary artery disease (CAD) on community health, noting its association with elevated incidences of recurrent ischemic events and mortality. The study specifically explores the contributing factors, clinical symptoms, angiographic findings, and management strategies for individuals aged 45 or younger who experience their initial ST-elevation myocardial infarction (STEMI). Methodology This observational study took place over a six-month period within the cardiology unit, involving 100 sequential patients diagnosed with STEMI. Results With a mean age of 42.5 years, the research had 100 patients, of which nine (9%) were under 25, 24 (24%) were between 26 and 35, and 67 (67%) were over 36. Of these, 89 (89%) were male. The following risk variables were found: obstructive CAD, smoking, being overweight, diabetes, hypertension, chest discomfort, and syncope. In 99 patients (99%), the most prevalent symptom was chest discomfort. Most often impacted was the left anterior descending (LAD) artery in 24 patients (24%), then the right coronary artery in 14 patients (14%). A total of 50 patients (50%) had percutaneous coronary intervention (PCI), with 15 patients (15%) undergoing elective PCI, 10 patients (10%) with pharmaco-invasive PCI, and 20 patients (20%) receiving primary PCI. In eight cases (8%), coronary artery bypass grafting (CABG) was required. Furthermore, 40 patients (40%) were under medical care, and 32 patients (32%) had recanalized and normal coronaries. No mortality was recorded in this study. Conclusions Acute myocardial infarction is most frequently seen in very young adult males, and the most common risk factor is smoking. The most common clinical manifestation, anterior wall myocardial infarction, was caused by the main source of involvement, the LAD artery. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Ethics Committee, Jagadguru Sri Shivarathreeshwara (JSS) Academy of Higher Education and Research issued approval IEC/JSSMC/2023/123. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Ramanathan et al.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu