The role of selected nutraceuticals in management of prediabetes and diabetes: An updated review of the literature. Part II.

Autor: Derosa G; Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.; Centre of Diabetes, Metabolic Diseases, and Dyslipidemias, University of Pavia, Pavia, Italy.; Regional Centre for Prevention, Surveillance, Diagnosis and Treatment of Dyslipidemias and Atherosclerosis, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Laboratory of Molecular Medicine, University of Pavia, Pavia, Italy., D'Angelo A; Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.; Laboratory of Molecular Medicine, University of Pavia, Pavia, Italy., Maffioli P; Centre of Diabetes, Metabolic Diseases, and Dyslipidemias, University of Pavia, Pavia, Italy.; Regional Centre for Prevention, Surveillance, Diagnosis and Treatment of Dyslipidemias and Atherosclerosis, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Jazyk: angličtina
Zdroj: Phytotherapy research : PTR [Phytother Res] 2024 Nov; Vol. 38 (11), pp. 5490-5532. Date of Electronic Publication: 2024 Oct 03.
DOI: 10.1002/ptr.8312
Abstrakt: We have already published a review about the results of clinical trials evaluating the effects of selected nutraceuticals on glycemia in humans. In this second part, we describe the role of other nutraceuticals involved in dysglycemia. The available evidence showed promising hypoglycemic effects of the nutraceuticals reviewed both for their efficacy and safety profile. However, contradictory results as regard the efficacy of some supplements such as Allium sativum, Juglans regia, and Lycium barbarum on glucose homeostasis have emerged from some clinical studies. Other nutraceuticals including Aloe vera, Amorphophallus Konjac, Bauhinia forficata, Coccinia, Ganoderma lucidum, Ipomoea batatas, and Lupinus mutabilis require larger and long-term studies rigorously designed to confirm their hypoglycemic effects due to the scarce data available and the poor quality of clinical trials. Further studies are also required for Cinnamomum, Cynara scolymus, Momordica charantia, Olea europaea, and Opuntia streptacantha. Moreover, well-designed large and long-term clinical trials including the use of standardized nutraceutical preparations are necessary for Phaseolus vulgaris and Vaccinium myrtillus.
(© 2024 The Author(s). Phytotherapy Research published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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