Stimulus duration encoding occurs early in the moth olfactory pathway.

Autor: Barta T; Department of Sensory Ecology, Institute of Ecology and Environmental Sciences of Paris, INRAE, Sorbonne Université, CNRS, IRD, UPEC, Université de Paris, Route de Saint Cyr, Versailles, 78000, France. tomas.barta@oist.jp.; Laboratory of Computational Neuroscience, Institute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, 14220, Czech Republic. tomas.barta@oist.jp.; Neural Coding and Brain Computing Unit, Okinawa Institute of Science and Technology, 1919-1 Tancha, Onna, 904-0412, Okinawa, Japan. tomas.barta@oist.jp., Monsempès C; Department of Sensory Ecology, Institute of Ecology and Environmental Sciences of Paris, INRAE, Sorbonne Université, CNRS, IRD, UPEC, Université de Paris, Route de Saint Cyr, Versailles, 78000, France., Demondion E; Department of Sensory Ecology, Institute of Ecology and Environmental Sciences of Paris, INRAE, Sorbonne Université, CNRS, IRD, UPEC, Université de Paris, Route de Saint Cyr, Versailles, 78000, France., Chatterjee A; Department of Sensory Ecology, Institute of Ecology and Environmental Sciences of Paris, INRAE, Sorbonne Université, CNRS, IRD, UPEC, Université de Paris, Route de Saint Cyr, Versailles, 78000, France., Kostal L; Laboratory of Computational Neuroscience, Institute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, 14220, Czech Republic. kostal@biomed.cas.cz., Lucas P; Department of Sensory Ecology, Institute of Ecology and Environmental Sciences of Paris, INRAE, Sorbonne Université, CNRS, IRD, UPEC, Université de Paris, Route de Saint Cyr, Versailles, 78000, France. philippe.lucas@inrae.fr.
Jazyk: angličtina
Zdroj: Communications biology [Commun Biol] 2024 Oct 03; Vol. 7 (1), pp. 1252. Date of Electronic Publication: 2024 Oct 03.
DOI: 10.1038/s42003-024-06921-z
Abstrakt: Pheromones convey rich ethological information and guide insects' search behavior. Insects navigating in turbulent environments are tasked with the challenge of coding the temporal structure of an odor plume, obliging recognition of the onset and offset of whiffs of odor. The coding mechanisms that shape odor offset recognition remain elusive. We designed a device to deliver sharp pheromone pulses and simultaneously measured the response dynamics from pheromone-tuned olfactory receptor neurons (ORNs) in male moths and Drosophila. We show that concentration-invariant stimulus duration encoding is implemented in moth ORNs by spike frequency adaptation at two time scales. A linear-nonlinear model fully captures the underlying neural computations and offers an insight into their biophysical mechanisms. Drosophila use pheromone cis-vaccenyl acetate (cVA) only for very short distance communication and are not faced with the need to encode the statistics of the cVA plume. Their cVA-sensitive ORNs are indeed unable to encode odor-off events. Expression of moth pheromone receptors in Drosophila cVA-sensitive ORNs indicates that stimulus-offset coding is receptor independent. In moth ORNs, stimulus-offset coding breaks down for short ( < 200 ms) whiffs. This physiological constraint matches the behavioral latency of switching from the upwind surge to crosswind cast flight upon losing contact with the pheromone.
(© 2024. The Author(s).)
Databáze: MEDLINE
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