Self-Matching Assembly of Chiral Gold Nanoparticles Leads to High Optical Asymmetry and Sensitive Detection of Adenosine Triphosphate.

Autor: Zhang NN; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.; Key Laboratory of Organ Regeneration and Transplantation of Ministry of Education, Institute of Immunology, The First Hospital, Jilin University, Changchun 130012, China., Mychinko M; EMAT and NANOlab Center of Excellence, University of Antwerp, 2020 Antwerp, Belgium., Gao SY; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China., Yu L; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China., Shen ZL; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China., Wang L; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China., Peng F; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China., Wei Z; Department of Organic Chemistry, College of Chemistry, Jilin University, Changchun 130012, China., Wang Z; Electron Microscopy Center, and Jilin Provincial International Cooperation Key Laboratory of High-Efficiency Clean Energy Materials, Key Laboratory of Automobile Materials MOE, Jilin University, Changchun 130012, China., Zhang W; Electron Microscopy Center, and Jilin Provincial International Cooperation Key Laboratory of High-Efficiency Clean Energy Materials, Key Laboratory of Automobile Materials MOE, Jilin University, Changchun 130012, China., Zhu S; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.; Joint Laboratory of Opto-Functional Theranostics in Medicine and Chemistry, The First Hospital, Jilin University, Changchun 130012, China., Yang Y; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China., Sun T; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.; Key Laboratory of Organ Regeneration and Transplantation of Ministry of Education, Institute of Immunology, The First Hospital, Jilin University, Changchun 130012, China., Liz-Marzán LM; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), 20014 Donostia-San Sebastián, Spain.; Ikerbasque, Basque Foundation for Science, 43009 Bilbao, Spain.; Networking Biomedical Research Center on Bioengineering Biomaterials and Nanomedicine (CIBER-BBN), 20014 Donostia-San Sebastián, Spain.; Cinbio, University of Vigo, 36310 Vigo, Spain., Bals S; EMAT and NANOlab Center of Excellence, University of Antwerp, 2020 Antwerp, Belgium., Liu K; State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.; Joint Laboratory of Opto-Functional Theranostics in Medicine and Chemistry, The First Hospital, Jilin University, Changchun 130012, China.
Jazyk: angličtina
Zdroj: Nano letters [Nano Lett] 2024 Oct 03. Date of Electronic Publication: 2024 Oct 03.
DOI: 10.1021/acs.nanolett.4c03782
Abstrakt: To achieve chiral amplification, life uses small chiral molecules as building blocks to construct hierarchical chiral architectures that can realize advanced physiological functions. Inspired by the chiral amplification strategy of nature, we herein demonstrate that the chiral assembly of chiral gold nanorods (GNRs) leads to enhanced optical asymmetry factors ( g -factors), up to 0.24. The assembly of chiral GNRs, dictated by structural self-matching, leads to g -factors with over 100-fold higher values than those of individual chiral GNRs, as confirmed by numerical simulations. Moreover, the efficient optical asymmetry of chiral GNR assemblies enables their application as highly sensitive sensors of adenosine triphosphate (ATP detection limit of 1.0 μM), with selectivity against adenosine diphosphate and adenosine monophosphate.
Databáze: MEDLINE