Clozapine monitoring requirements: is it time for an update?

Autor: Fernandez-Egea E; Cambridgeshire and Peterborough NHS Foundation Trust and Department of Psychiatry, University of Cambridge, Cambridge, UK., McCutcheon RA; Department of Psychiatry, University of Oxford, Oxford, Oxford Health NHS Foundation Trust, Oxford and Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, UK.
Jazyk: angličtina
Zdroj: The British journal of psychiatry : the journal of mental science [Br J Psychiatry] 2024 Oct 03, pp. 1-3. Date of Electronic Publication: 2024 Oct 03.
DOI: 10.1192/bjp.2024.150
Abstrakt: Oloyede and colleagues advocate for updating haematological monitoring requirements for clozapine, arguing that current protocols overestimate the risk of clozapine-induced agranulocytosis. Their research suggests that stringent monitoring may unnecessarily limit access to clozapine, a crucial treatment for resistant schizophrenia. The editorial supports calls for international consensus to carefully weigh the pros and cons of relaxing monitoring guidelines while ensuring comprehensive care for patients.
Databáze: MEDLINE