Prospective observational study on scar sequelae after MPOX infection: an analysis of 40 patients.

Autor: Grau-Echevarría A; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain.; Department of Medicine, University of Valencia, Valencia, Spain., Labrandero-Hoyos C; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain., Peñuelas-Leal R; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain., Finello M; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain., Blaya-Imbernón D; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain.; Department of Medicine, University of Valencia, Valencia, Spain., Magdaleno-Tapial J; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain., García ÁG; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain., Zafrilla EP; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain., García-García JÁ; Pathological Anatomy Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain., Cuenca LG; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain., Albiach AN; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain., Aguilera Arjona J; Department of Medicine and Dermatology, University of Málaga, Malaga, Spain., Ocete-Mochón MD; Microbiology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain., Díez-Recio E; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain., Hernández-Bel P; Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain.; Department of Medicine, University of Valencia, Valencia, Spain.
Jazyk: angličtina
Zdroj: International journal of dermatology [Int J Dermatol] 2024 Dec; Vol. 63 (12), pp. 1767-1773. Date of Electronic Publication: 2024 Oct 02.
DOI: 10.1111/ijd.17500
Abstrakt: Background: Monkeypox (MPOX) caused a public health emergency of international concern (PHEIC) outbreak between 2022 and 2023, with a recent rise in cases that prompted the World Health Organization (WHO) to declare the disease a PHEIC once again. There is little information on its long-term scarring sequelae.
Objectives: The objective of this study was to assess the risk and characteristics of scarring in patients with MPOX in a tertiary hospital.
Methods: This is a prospective cohort study including patients diagnosed using polymerase chain reaction (PCR) tests. Clinical data were collected and followed up at 12-15 months to assess scarring and its impact on quality of life.
Results: Of the 40 patients, 19 (47.5%) developed scars, which were more common in those with initial cutaneous manifestations. Scars significantly affected the quality of life, especially in the genital and mucosal areas. The limited sample and loss to follow-up may affect the validity of the results.
Conclusion: Scarring is a frequent and disfiguring sequela of MPOX, particularly in patients with early skin symptoms. Prevention and close follow-up are crucial in mitigating these complications.
(© 2024 The Author(s). International Journal of Dermatology published by Wiley Periodicals LLC on behalf of the International Society of Dermatology.)
Databáze: MEDLINE
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