The Impact of Orthodontic Adhesive Containing Resveratrol, Silver, and Zinc Oxide Nanoparticles on Shear Bond Strength: An In Vitro Study.

Autor:	Prasad T; Orthodontics and Dentofacial Orthopedics, School of Dental Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND., Pawar R; Orthodontics and Dentofacial Orthopedics, School of Dental Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND., Ganiger C; Orthodontics and Dentofacial Orthopedics, School of Dental Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND., Ronad Y; Orthodontics and Dentofacial Orthopedics, School of Dental Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND., Phaphe S; Orthodontics and Dentofacial Orthopedics, School of Dental Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND., Mane P; Orthodontics and Dentofacial Orthopedics, School of Dental Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND., Patil S; Orthodontics and Dentofacial Orthopedics, School of Dental Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Aug 31; Vol. 16 (8), pp. e68346. Date of Electronic Publication: 2024 Aug 31 (Print Publication: 2024).
DOI:	10.7759/cureus.68346
Abstrakt:	Introduction The goal of orthodontic treatment is to provide patients with esthetic smiles and functional occlusion. Despite best efforts and continuous evolution of materials, white spot lesions present a persistent hindrance to the desired treatment outcome. Nanoparticles have shown efficacy in reducing microbial activity; however, currently, there is a need for natural anti-cariogenic compounds with minimal side effects. Resveratrol is a natural compound belonging to the polyphenol group and has shown promising anti-microbial efficacy. This study aimed to evaluate the influence of dentin bonding agents incorporated with the following three different nanoparticles on shear bond strength: silver nanoparticles (Ag-Np), zinc oxide nanoparticles (ZnO-Np), and resveratrol nanoparticles (RSV-Np). Materials and methods A total of 40 premolar teeth therapeutically extracted were assigned to four equal groups of n=10 each. Groups 1, 2, and 3 used experimental adhesives doped with silver, zinc oxide, and resveratrol nanoparticles, respectively. Group 4 was bonded using unmodified adhesive. The bonded teeth were then subjected to shear bond strength (SBS) testing which was measured using a Universal Testing Machine (model no. UNITEST-10; Pune, India: ACME Engineers). Statistical analyses were performed using SPSS version 21 (Armonk, NY: IBM Corp.), employing one-way ANOVA and Tukey's post-hoc test for pairwise comparisons. Results Shear bond strength testing revealed that the control group with unmodified adhesive (8.6 MPa) had the highest SBS, followed by RSV-Np (7.6 MPa), Ag-Np (6.3 MPa), and ZnO-Np (5.65 MPa). Although the experimental groups demonstrated decreased SBS compared to the control, the values for Ag-Np and RSV-Np fell within the acceptable range. Conclusion Resveratrol nanoparticles had the least impact on shear bond strength among the experimental groups. These findings suggest that the incorporation of resveratrol nanoparticles in dentin bonding agents can provide anti-cariogenic effect without significantly impacting the adhesive's mechanical properties thereby providing a new and promising alternative to synthetic nanoparticles. Further studies are recommended to optimize the balance between anti-microbial efficacy and bond strength in clinical applications. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Ethics Committee of Krishna Vishwa Vidyapeeth (Deemed to be University) issued approval #KVVDU/IEC/08/2022. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Prasad et al.)
Databáze:	MEDLINE
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