The Power of a Complex Systems Perspective to Elucidate Aging.
| Autor: | Cohen AA; Robert N. Butler Columbia Aging Center and Department of Environmental Health Sciences, Columbia University, New York, New York, USA., Olde Rikkert MGM; Department of Geriatric Medicine, Radboud University Medical Center, Nijmegen, The Netherlands. |
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| Jazyk: | angličtina |
| Zdroj: | The journals of gerontology. Series A, Biological sciences and medical sciences [J Gerontol A Biol Sci Med Sci] 2024 Oct 01; Vol. 79 (10). |
| DOI: | 10.1093/gerona/glae210 |
| Abstrakt: | It is becoming highly accepted that aging, age-related diseases, and geriatric healthcare can move forward if reductionist research is complemented by integrative research uniting knowledge on specific aging mechanisms, multiple biomedical, social, psychological, lifestyle, and environmental factors and their interactions. In this special issue, we present exciting papers that illustrate how complexity science theory and practice can be applied to aging research and provide a better understanding and quantification of healthy aging and vulnerability to disease. Recent insights on biomarkers, clocks of aging, frailty, and resilience are covered and studied in interaction with a dynamic multiscale perspective. The editorial and closing viewpoint guide you through basic principles of gerontological complexity science and shed light on new research horizons, including innovative systems-based interventions. (© The Author(s) 2024. Published by Oxford University Press on behalf of The Gerontological Society of America.) |
| Databáze: | MEDLINE |
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