Native Hawaiian and Pacific Islander populations in genomic research.

Autor: Ha EK; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; University of Hawai'i at Mānoa, Honolulu, HI, USA.; University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Shriner D; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Callier SL; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Department of Clinical Research and Leadership, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Riley L; University of Hawai'i at Mānoa, Honolulu, HI, USA., Adeyemo AA; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. amy.bentley@nih.gov.
Jazyk: angličtina
Zdroj: NPJ genomic medicine [NPJ Genom Med] 2024 Sep 30; Vol. 9 (1), pp. 45. Date of Electronic Publication: 2024 Sep 30.
DOI: 10.1038/s41525-024-00428-6
Abstrakt: The role of genomic research and medicine in improving health continues to grow significantly, highlighting the need for increased equitable inclusion of diverse populations in genomics. Native Hawaiian and Pacific Islander (NHPI) communities are often missing from these efforts to ensure that the benefits of genomics are accessible to all individuals. In this article, we analyze the qualities of NHPI populations relevant to their inclusion in genomic research and investigate their current representation using data from the genome-wide association studies (GWAS) catalog. A discussion of the barriers NHPI experience regarding participating in research and recommendations to improve NHPI representation in genomic research are also included.
(© 2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.)
Databáze: MEDLINE
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