Diet and Caries-associated Bacteria in Severe Early Childhood Caries An In vitro Study.

Autor:	Pidamale R; Department of Pediatric Dentistry, KVG Dental College and Hospital, Kurunjibhag, Sullia, Karnataka, India., Chauhan PS; Department of Pediatric and Preventive Dentistry, Sharda Dental Clinic, Plot No 58/1. O.u.t. Colony Sainikpuri, Secunderabad, Telengana, India., Singh R; Department of Pediatric and Preventive Dentistry, Purvanchal Institute of Dental Sciences, GIDA, Gorakhpur, Uttar Pradesh, India., Imran MD; Department of Paediatric and Preventive Dentistry, Patna Medical College and Hospital, Ashok Raj Path, Patna, Bihar, India., Prakash R; Oral Patholgy and Microbiology, College of Dental Sciences Amargadh, Bhavnagar, Gujarat, India., Kuppusamy K; Public Health Dentistry, Indira Gandhi Institute of Dental Sciences, Puducherry, India.
Jazyk:	angličtina
Zdroj:	Journal of pharmacy & bioallied sciences [J Pharm Bioallied Sci] 2024 Jul; Vol. 16 (Suppl 3), pp. S2664-S2666. Date of Electronic Publication: 2024 Jul 18.
DOI:	10.4103/jpbs.jpbs_363_24
Abstrakt:	Background: Severe Early Childhood Caries (S-ECC) is a prevalent oral health issue among young children, often associated with specific caries-associated bacteria. This in vitro study investigates the impact of diet on the growth and activity of caries-associated bacteria in S-ECC. Materials and Methods: Plaque samples of Streptococcus mutans and Lactobacillus species were procured from laboratory. The samples were exposed to different dietary conditions, including high-sugar, high-carbohydrate, and control diets. The growth kinetics of caries-associated bacteria, including S. mutans and Lactobacillus species, were monitored using quantitative polymerase chain reaction (qPCR) and colony-forming unit (CFU) assays. Results: Under high-sugar conditions, the growth of S. mutans increased by 50% compared to the control group, as evidenced by qPCR analysis. Lactobacillus species also exhibited a significant increase in CFU counts in response to high-carbohydrate diets, showing a 40% rise compared to controls. Conclusion: This in vitro study highlights the influence of diet on the proliferation of caries-associated bacteria in severe early childhood caries. High-sugar and high-carbohydrate diets contribute to the growth and activity of S. mutans and Lactobacillus species, exacerbating the progression of dental caries in affected children. Competing Interests: There are no conflicts of interest. (Copyright: © 2024 Journal of Pharmacy and Bioallied Sciences.)
Databáze:	MEDLINE
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