Canine exfoliative cutaneous lupus erythematosus in two mixed breed littermates.

Autor: Dumitrache MO; Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, Cluj-Napoca, Romania.; Department of Clinical Sciences, Université de Toulouse, ENVT, Toulouse, France., Ursache AL; Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, Cluj-Napoca, Romania., Toma C; Department of Pathology, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Cluj-Napoca, Romania., Negoescu A; Department of Pathology, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Cluj-Napoca, Romania., Rietmann SJ; Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.; Dermfocus, University of Bern, Bern, Switzerland., Leeb T; Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.; Dermfocus, University of Bern, Bern, Switzerland., Cadiergues MC; Department of Clinical Sciences, Université de Toulouse, ENVT, Toulouse, France.; INFINITy, Inserm, CNRS, UPS, Université de Toulouse, Toulouse, France.
Jazyk: angličtina
Zdroj: Veterinary dermatology [Vet Dermatol] 2024 Sep 30. Date of Electronic Publication: 2024 Sep 30.
DOI: 10.1111/vde.13301
Abstrakt: Canine exfoliative cutaneous lupus erythematosus (ECLE) is the rarest variant of cutaneous lupus in dogs and has strong breed predilections. This report presents the clinical, histopathological and immunohistochemical features of two ECLE cases in mixed breed littermates and confirms the expected genetic mutation. A therapeutic response to oclacitinib also is documented.
(© 2024 ESVD and ACVD.)
Databáze: MEDLINE
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