Delayed DNase-I Administration but Not Gasdermin-D Inhibition Induces Hemorrhagic Transformation After Transient Focal Cerebral Ischemia in Mice.

Autor: Yin D; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.).; Center for Translational and Behavioral Neurosciences, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.)., Wang C; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.).; Center for Translational and Behavioral Neurosciences, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.)., Singh V; Institute of Experimental Immunology and Imaging, University Hospital Essen, University of Duisburg-Essen, Germany (V.S., A.A.T., M.G.)., Tuz AA; Institute of Experimental Immunology and Imaging, University Hospital Essen, University of Duisburg-Essen, Germany (V.S., A.A.T., M.G.)., Doeppner TR; Department of Neurology, University Hospital Gießen, Justus-Liebig-University Gießen, Germany (T.R.D.)., Gunzer M; Institute of Experimental Immunology and Imaging, University Hospital Essen, University of Duisburg-Essen, Germany (V.S., A.A.T., M.G.).; Leibniz-Institut für Analytische Wissenschaften e.V. (ISAS), Dortmund, Germany (M.G.)., Hermann DM; Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.).; Center for Translational and Behavioral Neurosciences, University Hospital Essen, University of Duisburg-Essen, Germany (D.Y., C.W., D.M.H.).
Jazyk: angličtina
Zdroj: Stroke [Stroke] 2024 Nov; Vol. 55 (11), pp. e297-e299. Date of Electronic Publication: 2024 Sep 30.
DOI: 10.1161/STROKEAHA.124.047862
Abstrakt: Competing Interests: Dr Gunzer reports compensation from Lead Discovery Center for consultant services. The other authors report no conflicts.
Databáze: MEDLINE