| Autor: |
Takayama Y; Okinawa Prefecture Commission for Epidemiological and Statistical Analysis, Japan.; Division of Infectious Diseases, Department of Internal Medicine, Okinawa Prefectural Chubu Hospital, Japan.; Graduate School of Biomedical Sciences, Nagasaki University, Japan., Shimakawa Y; Okinawa Prefecture Commission for Epidemiological and Statistical Analysis, Japan.; Institut Pasteur, France.; Pasteur International Unit at Kumamoto University / National Center for Global Health and Medicine, Japan., Aizawa Y; Public Kumejima Hospital, Japan., Butcher C; Molecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Japan., Chibana N; Division of Internal Medicine, Naha City Hospital, Japan., Collins M; Research Support Division, Occupational Health and Safety, OIST, Japan.; Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, United Kingdom., Kamegai K; Division of Infectious Diseases, Okinawa Prefectural Yaeyama Hospital, Japan., Kim TG; Molecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Japan.; Vaccine Commercialization Center, Gyeongbuk Institute for Bio industry, Republic of Korea., Koyama S; Emergency Department, Okinawa Prefectural Miyako Hospital, Japan., Matsuyama R; Okinawa Prefecture Commission for Epidemiological and Statistical Analysis, Japan.; Rakuno Gakuen Univerisity, Japan., Matthews MM; Molecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Japan., Mori T; Research Support Division, Occupational Health and Safety, OIST, Japan., Nagamoto T; Okinawa Prefecture Commission for Epidemiological and Statistical Analysis, Japan.; Graduate School of Informatics, Kyoto University, Japan., Narita M; Division of Infectious Diseases, Department of Internal Medicine, Okinawa Prefectural Chubu Hospital, Japan.; Division of Infectious Diseases, Department of Internal Medicine, Okinawa Prefectural Nambu Medical Center & Children's Medical Center, Japan., Omori R; Okinawa Prefecture Commission for Epidemiological and Statistical Analysis, Japan.; Division of Bioinformatics, International Institute for Zoonosis Control, Hokkaido University, Japan., Shibata N; Molecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Japan.; Division of Bacteriology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Japan., Shibata S; Molecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Japan.; Division of Bacteriology, Department of Microbiology and Immunology, Faculty of Medicine, Tottori University, Japan., Shiiki S; Division of Infectious Diseases, Department of Internal Medicine, Okinawa Prefectural Chubu Hospital, Japan., Takakura S; Division of Infectious Diseases, Department of Internal Medicine, Okinawa Prefectural Chubu Hospital, Japan., Toyozato N; Division of Infectious Diseases, Department of Internal Medicine, Okinawa Prefectural Chubu Hospital, Japan.; Emergency and critical care center, Okinawa Prefectural Chubu Hospital, Japan., Tsuchiya H; Department of Emergency and Critical Care Medicine, Okinawa Prefectural Nambu Medical Center & Children's Medical Center, Japan., Wolf M; Molecular Cryo-Electron Microscopy Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Japan., Yamamoto T; Graduate School of Biomedical Sciences, Nagasaki University, Japan., Yokoyama S; Division of Infectious Diseases, Department of Internal Medicine, Okinawa Prefectural Chubu Hospital, Japan., Yonaha S; Public Kumejima Hospital, Japan., Mizumoto K; Okinawa Prefecture Commission for Epidemiological and Statistical Analysis, Japan.; Graduate School of Advanced Integrated Studies in Human Survivability, Kyoto University, Japan.; Hakubi Center for Advanced Research, Kyoto University, Japan. |
| Abstrakt: |
We estimated the seroprevalence of anti-SARS-COV-2 IgG in different island groups in Okinawa. A cross-sectional sero-survey was repeated in three periods between July 2020 and February 2021. A total of 2683 serum samples were collected from six referral medical centers, each covering a separate region in Okinawa. In the main island, the seroprevalence was 0.0% (0/392, 95% CI: 0.0-0.9), 0.6% (8/1448, 0.2-1.1), and 1.4% (8/582, 0.6-2.7) at the 1 st , 2 nd , and 3 rd sero-survey, respectively. In the remote islands, the seroprevalence was 0.0% (0/144, 95% CI: 0.0-2.5) and 1.6% (2/123, 0.2-5.8) at the 2 nd and 3 rd survey, respectively. The case detection ratio was 2.7 (95% CI: 1.3-5.3) in the main island and 2.8 (0.7-11.1) in the remote islands during the 3 rd survey. The case detection ratio was the highest in people aged 20-29 years (8.3, 95% CI: 3.3-21.4) in the main island and in those aged 50-59 years (14.1, 2.1-92.7) in the remote islands, suggesting under-reporting of clinical cases by the surveillance system in these subgroups. A sero-survey during an emerging infectious disease epidemic can be useful for validating the reliability of the surveillance system by providing the case detection ratio. |
