Impact of sarcopenic obesity on surgical complications and oncologic outcomes of upper gastrointestinal tumors: A systematic review and meta-analysis.

Autor: Juez LD; Department of General and Digestive Surgery, Hospital Universitario Ramón y Cajal, Facultad de Medicina, Universidad de Alcalá, IRYCIS. Madrid, Spain. Electronic address: luz.juez@gmail.com., Ortega ADC; Department of General and Digestive Surgery, Hospital Universitario Ramón y Cajal, Facultad de Medicina, Universidad de Alcalá, IRYCIS. Madrid, Spain., Priego P; Department of General and Digestive Surgery, Hospital Universitario La Paz, Facultad de Medicina, Universidad Autónoma de Madrid, Spain., Pérez JCG; Department of General and Digestive Surgery, Hospital Universitario Ramón y Cajal, Facultad de Medicina, Universidad de Alcalá, IRYCIS. Madrid, Spain., Fernández-Cebrián JM; Department of General and Digestive Surgery, Hospital Universitario Ramón y Cajal, Facultad de Medicina, Universidad de Alcalá, IRYCIS. Madrid, Spain., Botella-Carretero JI; Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Facultad de Medicina, Universidad de Alcalá, IRYCIS. Madrid, Spain.
Jazyk: angličtina
Zdroj: Cirugia espanola [Cir Esp (Engl Ed)] 2024 Sep 27. Date of Electronic Publication: 2024 Sep 27.
DOI: 10.1016/j.cireng.2024.09.005
Abstrakt: Sarcopenic obesity (SO) is a new entity whose definition encompasses the diagnosis of overweight in malnourished patients. The aim of the review was to assess the impact of body composition in patients with esophago-gastric tumors (EGT) on perioperative and oncological outcomes. This systematic review was conducted under the PRISMA guidelines. MEDLINE (PubMed), Embase, Web of Science and SCOPUS databases were searched until January 2024. Sixteen articles were identified for analysis analyzing 5,378 patients. The prevalence of SO was 10% (95%CI: 6-16; I 2 = 94%). Preoperative diagnosis of SO was associated with a twofold increased risk of severe postoperative complications (OR 2.32 [95%CI 1.41-3.82] I 2 = 70%). Meta-analysis of overall survival outcomes identified that SO was associated with worse overall survival (HR 2.30; 95%CI 1.46-3.61).
(Copyright © 2024. Published by Elsevier España, S.L.U.)
Databáze: MEDLINE
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