| Autor: |
Baran AI; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Van Yuzuncu Yıl University, Van 65080, Turkey., Binici I; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Van Yuzuncu Yıl University, Van 65080, Turkey., Arslan Y; Department of Infectious Diseases and Clinical Microbiology, Batman Training and Research Hospital, Batman 72000, Turkey., Hakseven Karaduman Z; Department of Infectious Diseases and Clinical Microbiology, Van Training and Research Hospital, Van 65300, Turkey., Ilter S; Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Van Yuzuncu Yıl University, Van 65090, Turkey., Tarcan T; Department of Infectious Diseases and Clinical Microbiology, Tatvan State Hosptial, Bitlis 13000, Turkey., Unal M; Department of Infectious Diseases and Clinical Microbiology, Nusaybin State Hosptial, Mardin 47300, Turkey. |
| Abstrakt: |
Infectious spondylodiscitis is a life-threatening disease and has some challenges in terms of diagnostic, differentiative, and therapeutic processes. Therefore, rapid and effective management of infectious spondylodiscitis is necessary. Hematological inflammation indices (HIIs) such as the neutrophil/lymphocyte ratio and aggregate index of systemic inflammation are derived from blood cells and used as diagnostic, prognostic, predictive, and treatment monitoring indicators. This study aimed to evaluate HIIs for discriminating between infectious spondylodiscitis pathogens. This retrospective comparative study included 116 patients with infectious spondylodiscitis. According to the responsible infectious pathogens, three types of infectious spondylodiscitis were defined: Brucella (n = 51), pyogenic (n = 43), and tuberculous (n = 22). The HIIs were derived from baseline complete blood counts. The three types of infectious spondylodiscitis were statistically compared for the HII scores. We found that the Brucella group had significantly lower HII scores than the pyogenic group ( p < 0.05). Also, the Brucella group had significantly lower HII scores than the tuberculous group ( p < 0.05). However, no significant differences were found between the pyogenic and tuberculous groups regarding HIIs ( p > 0.05). In conclusion, the HIIs may be considered in the differentiation between Brucella spondylodiscitis and other types of infectious spondylodiscitis. |
