What's new in neuropathology 2024: CNS WHO 5th edition updates.

Autor: Smith H; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Ahrendsen JT; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Jazyk: angličtina
Zdroj: Journal of pathology and translational medicine [J Pathol Transl Med] 2024 Sep 30. Date of Electronic Publication: 2024 Sep 30.
DOI: 10.4132/jptm.2024.09.11
Abstrakt: The fifth edition of the World Health Organization (WHO) Classification of Central Nervous System (CNS) Tumors was released in 2021, just five years following the updated fourth edition. Advanced molecular testing such as next-generation sequencing, RNA fusion analysis, and DNA methylation profiling has led to more precise grading and classification of pre-existing tumor types as well as the recognition of new ones. Herein, we outline the major updates of the 2021 WHO Classification of CNS tumors, with emphasis on the expanded molecular characterization of CNS tumors.
Databáze: MEDLINE