Mental illness and COVID-19 vaccination: a multinational investigation of observational & register-based data.

Autor: Barker MM; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. mary.barker@ki.se., Kõiv K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Magnúsdóttir I; Centre of Public Health Sciences, Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Milbourn H; Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, United Kingdom., Wang B; PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.; Department of Child Health and Development, Norwegian Institute of Public Health, Oslo, Norway., Du X; Department of Psychology, University of Oslo, Oslo, Norway.; Modum Bad Psychiatric Hospital and Research Center, Oslo, Vikersund, Norway., Murphy G; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Herweijer E; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Gísladóttir EU; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Li H; School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Lovik A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Institute of Psychology, Leiden University, Leiden, The Netherlands., Kähler AK; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, United Kingdom., Feychting M; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hauksdóttir A; Centre of Public Health Sciences, Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Joyce EE; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Thordardottir EB; Centre of Public Health Sciences, Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Frans EM; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Hoffart A; Department of Psychology, University of Oslo, Oslo, Norway.; Modum Bad Psychiatric Hospital and Research Center, Oslo, Vikersund, Norway., Mägi R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Tómasson G; Centre of Public Health Sciences, Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Rheumatology, University Hospital, Reykjavik, Iceland., Ásbjörnsdóttir K; Centre of Public Health Sciences, Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Jakobsdóttir J; Centre of Public Health Sciences, Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Andreassen OA; NORMENT Centre, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Oslo University Hospital, Oslo, Norway., Sullivan PF; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Genetics and Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Johnson SU; Department of Psychology, University of Oslo, Oslo, Norway.; Modum Bad Psychiatric Hospital and Research Center, Oslo, Vikersund, Norway., Aspelund T; Centre of Public Health Sciences, Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Brandlistuen RE; Department of Child Health and Development, Norwegian Institute of Public Health, Oslo, Norway.; The Norwegian Mother, Father and Child Cohort Study, Norwegian Institute of Public Health, Oslo, Norway., Ask H; PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway., McCartney DL; Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, United Kingdom., Ebrahimi OV; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.; Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom., Lehto K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Valdimarsdóttir UA; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre of Public Health Sciences, Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA., Nyberg F; School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Fang F; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Jazyk: angličtina
Zdroj: Nature communications [Nat Commun] 2024 Sep 26; Vol. 15 (1), pp. 8124. Date of Electronic Publication: 2024 Sep 26.
DOI: 10.1038/s41467-024-52342-1
Abstrakt: Individuals with mental illness are at higher risk of severe COVID-19 outcomes. However, previous studies on the uptake of COVID-19 vaccination in this population have reported conflicting results. Using data from seven cohort studies (N = 325,298) included in the multinational COVIDMENT consortium, and the Swedish registers (N = 8,080,234), this study investigates the association between mental illness (defined using self-report measures, clinical diagnosis and prescription data) and COVID-19 vaccination uptake. Results from the COVIDMENT cohort studies were pooled using meta-analyses, the majority of which showed no significant association between mental illness and vaccination uptake. In the Swedish register study population, we observed a very small reduction in the uptake of both the first and second dose of a COVID-19 vaccine among individuals with vs. without mental illness; the reduction was however greater among those not using psychiatric medication. Here we show that uptake of the COVID-19 vaccine is generally high among individuals both with and without mental illness, however the lower levels of vaccination uptake observed among subgroups of individuals with unmedicated mental illness warrants further attention.
(© 2024. The Author(s).)
Databáze: MEDLINE
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