Prevalence status and detection of benzimidazole resistance using AS-PCR in Haemonchus contortus of goats from Marathwada region, Maharashtra, India.

Autor: Bhagat V; Department of Veterinary Parasitology, College of Veterinary & Animal Sciences, MAFSU, Parbhani, Maharashtra, India., Bhong C; Department of Veterinary Public Health and Epidemiology, KNP college of Veterinary Science, MAFSU, Shirwal, Maharashtra, India., Khillare B; Department of Veterinary Parasitology, College of Veterinary & Animal Sciences, MAFSU, Parbhani, Maharashtra, India., Jadhav N; Department of Veterinary Pharmacology & Toxicology, College of Veterinary & Animal Sciences, MAFSU, Parbhani, Maharashtra, India., Narawade M; Department of Veterinary Parasitology, College of Veterinary & Animal Sciences, MAFSU, Parbhani, Maharashtra, India., Khandekar G; Department of Veterinary Surgery & Radiology, Mumbai Veterinary College, MAFSU, Mumbai, Maharashtra, India., Gaikwad S; Department of Veterinary Surgery & Radiology, Mumbai Veterinary College, MAFSU, Mumbai, Maharashtra, India., Katkade B; Department of Animal Genetics & Breeding, College of Veterinary & Animal Sciences, MAFSU, Parbhani, Maharashtra, India., Sharma AK; School of Agriculture, Uttaranchal University, Dehradun, -248007, Uttarakhand, India., Chigure G; Department of Veterinary Parasitology, College of Veterinary & Animal Sciences, MAFSU, Parbhani, Maharashtra, India. Electronic address: gajananchigure@mafsu.in.
Jazyk: angličtina
Zdroj: Veterinary parasitology, regional studies and reports [Vet Parasitol Reg Stud Reports] 2024 Oct; Vol. 55, pp. 101119. Date of Electronic Publication: 2024 Sep 19.
DOI: 10.1016/j.vprsr.2024.101119
Abstrakt: This study examined Haemonchus contortus prevalence and benzimidazole resistance in eight districts of Marathwada, Maharashtra, India. A comprehensive investigation of 264 abomasa of goats collected from abattoirs and goats necropsied at the College of Veterinary Sciences and Animal Husbandry, Parbhani, revealed 21.21 % a prevalence of H. contortus. The incidence of H. contortus did not vary much across seasons and it was highest in summer (23.42 %), followed by monsoon (22.89 %), and lowest in winter (15.71 %). Statistically non-significant (p < 0.05) prevalence was observed in male and female animals. A detailed examination of 168 adult H. contortus worms from eight districts revealed the presence of all conceivable genotypes including homozygous resistant (rr), susceptible (SS), and heterozygous (Sr) BZ susceptible genotypes. The rr was the most frequent at 50 %, followed by SS at 27 % and Sr at 22 %. The presence of the SNP was observed in in all eight randomly selected and sequenced samples.
Competing Interests: Declaration of competing interest The authors affirm that they do not possess any identifiable conflicting financial or personal interests that could have potentially influenced the findings presented in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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