Viral etiologies of acute liver failure.

Autor:	McSteen BW; Department of Medicine, New York-Presbyterian/Weill Cornell Campus, New York, NY 10021, United States. qqq9001@nyp.org., Ying XH; Department of Medicine, New York-Presbyterian/Weill Cornell Campus, New York, NY 10021, United States., Lucero C; Department of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, NY 10021, United States., Jesudian AB; Department of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, NY 10021, United States.
Jazyk:	angličtina
Zdroj:	World journal of virology [World J Virol] 2024 Sep 25; Vol. 13 (3), pp. 97973.
DOI:	10.5501/wjv.v13.i3.97973
Abstrakt:	Acute liver failure (ALF) is a rare cause of liver-related mortality worldwide, with an estimated annual global incidence of more than one million cases. While drug-induced liver injury, including acetaminophen toxicity, is the leading cause of ALF in the Western world, viral infections remain a significant cause of ALF and the most common cause in many developing nations. Given the high mortality rates associated with ALF, healthcare providers should be aware of the broad range of viral infections that have been implicated to enable early diagnosis, rapid treatment initiation when possible, and optimal management, which may include liver transplantation. This review aims to provide a summary of viral causes of ALF, diagnostic approaches, treatment options, and expected outcomes. Competing Interests: Conflict-of-interest statement: Jesudian AB received consulting and speaking for Salix Pharmaceuticals, consulting for Dynavax Therapeutics, and speaking for Madrigal Pharmaceuticals. McSteen BW, Ying XH, and Lucero C have no financial conflicts to report. (©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.)
Databáze:	MEDLINE
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