The Use of Focused Ultrasound Ablation for Movement Disorders.

Autor:	Silva N; Department of Neurosurgery, University of North Carolina, 170 Manning Drive, Suite #2149, Chapel Hill, NC 27499, USA. Electronic address: https://twitter.com/NicoleAASilva., Green M; East Carolina University, School of Medicine., Roque D; UNC Movement Disorders Neuromodulation Program, Movement Disorders, Department of Neurology, University of North Carolina, 170 Manning Drive, Campus Box 7025, Chapel Hill, NC 27599, USA., Krishna V; Department of Neurosurgery, University of North Carolina, 170 Manning Drive, Suite #2149, Chapel Hill, NC 27499, USA. Electronic address: vibhor_krishna@med.unc.edu.
Jazyk:	angličtina
Zdroj:	Magnetic resonance imaging clinics of North America [Magn Reson Imaging Clin N Am] 2024 Nov; Vol. 32 (4), pp. 651-659. Date of Electronic Publication: 2024 Jul 29.
DOI:	10.1016/j.mric.2024.04.003
Abstrakt:	Focused ultrasound ablation achieves selective thermal lesioning of the thalamic and basal ganglia targets using real-time MR imaging guidance. It is US Food and Drug Administration-approved to treat essential tremor and Parkinson's disease tremor, fluctuations, and dyskinesias. Patients often seek focused ultrasound treatment because symptom relief is immediate, and hardware implantation is not required. This review summarizes the current and potential future application of focused ultrasound ablation to treat movement disorders. We also discuss the ongoing research optimizing the technique of focused ultrasound ablation to improve long-term efficacy and minimize the risk of side effects. Competing Interests: Disclosures Dr V. Krishna is funded by NIH, United States. All other authors do not have commercial or financial conflicts of interest, and there are no funding sources for all authors. (Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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