Good laboratory practice for PGT-M: Turkish Society of Reproductive Medicine guidelines.

Autor: Unsal E; Yale Fertility Center, Orange, CT, USA; Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT, USA. Electronic address: evrim.unsal@yale.edu., Aktuna S; Mikrogen Genetic Diagnosis Centre, Ankara, Turkey., Arda B; Ankara University Faculty of Medicine, Department of History of Medicine and Ethics, Ankara, Turkey., Balaban B; American Hospital Assisted Reproductive Technologies Unit, Istanbul, Turkey; Memorial Sisli Hospital, IVF and Reproductive Health Centre, Istanbul, Turkey., Baltaci V; Mikrogen Genetic Diagnosis Centre, Ankara, Turkey., Bayram A; ART Fertility Clinics, Abu Dhabi, United Arab Emirates., Bozdag G; Bahceci Health Group, Istanbul, Turkey., Candan ZN; Bruksel IVF Centre, Istanbul, Turkey., Cetinkaya M; Memorial Sisli Hospital, IVF and Reproductive Health Centre, Istanbul, Turkey., Ceylaner S; Intergen Genetic Diagnosis Centre, Ankara, Turkey., Findikli N; Erasme Hospital Infertility Clinic, Free University of Brussels, Brussels, Belgium., Goksever Celik H; Acibadem University, Department of Obstetrics and Gynecology, Acibadem Fulya Hospital IVF and Endometriosis Center, Istanbul, Turkey., Halicigil C; Yale Fertility Center, Orange, CT, USA; Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT, USA., Kahraman S; Memorial Sisli Hospital, IVF and Reproductive Health Centre, Istanbul, Turkey., Kayacaglayan M; Kayacağlayan Law Office, Ankara, Turkey., Keles I; Koc University Hospital IVF and Reproductive Health Centre, Istanbul, Turkey., Kurtoglu A; Ankara University Faculty of Medicine, Department of History of Medicine and Ethics, Ankara, Turkey., Mutlu A; Igenomix Turkiye, Istanbul, Turkey., Ozgon G; Nesiller Genetic Diagnosis Centre, Istanbul, Turkey., Sukur YE; Ankara University Faculty of Medicine, Department of Obstetrics and Gynaecology, Ankara, Turkey., Tufekci MA; Memorial Sisli Hospital, IVF and Reproductive Health Centre, Istanbul, Turkey., Yakin K; Koc University Hospital IVF and Reproductive Health Centre, Istanbul, Turkey., Yelke H; Memorial Sisli Hospital, IVF and Reproductive Health Centre, Istanbul, Turkey., Yildiz S; Koc University Hospital IVF and Reproductive Health Centre, Istanbul, Turkey., Ata B; ART Fertility Clinics, Dubai, United Arab Emirates; Koc University Faculty of Medicine, Department of Obstetrics and Gynaecology, Istanbul, Turkey.
Jazyk: angličtina
Zdroj: Reproductive biomedicine online [Reprod Biomed Online] 2024 Dec; Vol. 49 (6), pp. 104378. Date of Electronic Publication: 2024 Aug 03.
DOI: 10.1016/j.rbmo.2024.104378
Abstrakt: This guideline was prepared by the Turkish Society of Reproductive Medicine to define the conditions and requirements for an outsourced preimplantation genetic testing (PGT) programme in line with the experience and needs of practitioners. This guideline is intended to be a reference document for assisted reproductive technology centres, genetic diagnosis centres, non-governmental organizations working on reproductive health, legal experts, consultants working on laboratory accreditation, academicians specializing in ethical issues, and policy makers. The Consortium aims to provide recommendations addressing the challenges of genetic testing, especially PGT for monogenic diseases (PGT-M) due to the high rate of consanguineous marriage in Turkey. For this purpose, this summary document specifically includes challenges and recommendations regarding PGT-M practice, and aims to identify and aid in prevention of errors leading to misdiagnosis. The recommendations can be modified to fit other locations.
(Copyright © 2024 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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