Neurovascular coupling during dynamic upper body resistance exercise in healthy individuals.

Autor: Korad S; School of Health Sciences, Massey University, Wellington, New Zealand., Mündel T; School of Sport, Exercise and Nutrition, Massey University, Palmerston North, New Zealand.; Department of Kinesiology, Brock University, St Catharines, Ontario, Canada., Perry BG; School of Health Sciences, Massey University, Wellington, New Zealand.
Jazyk: angličtina
Zdroj: Experimental physiology [Exp Physiol] 2024 Dec; Vol. 109 (12), pp. 2017-2025. Date of Electronic Publication: 2024 Sep 25.
DOI: 10.1113/EP091970
Abstrakt: During unilateral static and rhythmic handgrip exercise, middle cerebral artery blood velocity (MCAv) increases in the contralateral side to the exercising limb. However, whether this neurovascular coupling-mediated increase in contralateral MCAv is apparent against a background of fluctuating perfusion pressure produced by dynamic resistance exercise (RE) is unclear. We examined the cerebral haemodynamic response to unilateral dynamic RE in 30 healthy individuals (female = 16, mean ± SD: age, 26 ± 6 years; height, 175 ± 10 cm; weight, 74 ± 15 kg; body mass index, 24 ± 5 kg m -2 ). Participants completed four sets of 10 paced repetitions (15 repetitions min -1 ) of unilateral bicep curl exercise at 60% of the predicted one-repetition maximum (7 ± 3 kg). Beat-to-beat blood pressure, bilateral MCAv and end-tidal carbon dioxide were measured throughout. One-way ANOVA was used to analyse cardiovascular variables and two-way ANOVA to analyse dependent cerebrovascular variables (side × sets, 2 × 5). A linear mixed model analysis was also performed to investigate the effects of end-tidal carbon dioxide and mean arterial blood pressure on MCAv. In comparison to baseline, within-exercise mean arterial blood pressure increased (P < 0.001) across the sets, whereas bilateral MCAv decreased (P < 0.001). However, no significant interaction effect was observed for any dependent variables (all P > 0.787). The linear mixed model revealed that end-tidal carbon dioxide had the greatest effect on MCAv (estimate = 1.019, t = 8.490, P < 0.001). No differences were seen in contralateral and ipsilateral MCAv during dynamic RE, suggesting that neurovascular coupling contributions during dynamic RE might be masked by other regulators, such as blood pressure.
(© 2024 The Author(s). Experimental Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society.)
Databáze: MEDLINE
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