Acute Respiratory Failure Requiring Invasive Ventilation in Adults With Congenital Syringomyelia/Arnold-Chiari Malformations: A Systematic Review.

Autor: Hamal D; Critical Care Medicine, King's College Hospital NHS Foundation Trust, London, GBR., Fernandes A; Trauma and Orthopedics, Lewisham and Greenwich NHS Trust, London, GBR., Ghimire P; Neurological Surgery, King's College Hospital NHS Foundation Trust, London, GBR., Wong A; Critical Care Medicine, King's College Hospital NHS Foundation Trust, London, GBR.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Sep 24; Vol. 16 (9), pp. e70109. Date of Electronic Publication: 2024 Sep 24 (Print Publication: 2024).
DOI: 10.7759/cureus.70109
Abstrakt: Arnold-Chiari malformations (ACM) and congenital syringomyelia/syrinx are rare neurological phenomenons that can present as acute respiratory failure and contribute to multiple extubation failures despite surgical intervention. A systematic review was conducted to scrutinize the current literature, screening 65 papers and including 12 papers (13 patients). Sixty-one percent of patients had type 1 ACM and 70% had a congenital syringomyelia. Neurosurgical intervention occurred in seven patients, five patients had at least one extubation failure which was due to apnea or reoccurrence of respiratory failure, and eight patients needed tracheostomies. The neurosurgical intervention aims to improve patient symptoms, but our data and current literature suggest that patients with these pathologies still undergo long ventilation weans and are not liberated from the ventilator due to ongoing respiratory failure.
Competing Interests: Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Hamal et al.)
Databáze: MEDLINE