The lifestyle and nutritional factors for dry eye disease in depression population: a retrospective case-control study.

Autor: Lee CY; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Nobel Eye Institute, Taipei, Taiwan.; Department of Ophthalmology, Jen-Ai Hospital Dali Branch, Taichung, Taiwan., Yang SF; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan., Lian IB; Institute of Statistical and Information Science, National Changhua University of Education, Changhua, Taiwan., Chang YL; Department of Medical Education, Cathay General Hospital, Taipei, Taiwan., Jhan YN; Institute of Statistical and Information Science, National Changhua University of Education, Changhua, Taiwan., Chang CK; Nobel Eye Institute, Taipei, Taiwan.; Department of Optometry, Da-Yeh University, Chunghua, Taiwan.
Jazyk: angličtina
Zdroj: Frontiers in medicine [Front Med (Lausanne)] 2024 Sep 10; Vol. 11, pp. 1376938. Date of Electronic Publication: 2024 Sep 10 (Print Publication: 2024).
DOI: 10.3389/fmed.2024.1376938
Abstrakt: Background: We aim to evaluate lifestyle and nutritional factors that lead to dry eye disease (DED) in a depressed population using data from the Taiwan BioBank (TWB).
Methods: A retrospective case-control study was conducted, and patients with depression based on a questionnaire were selected as the depression group. Each patient in the depression group was matched by age and sex to two individuals without depression, and a total of 3,754 and 7,508 patients constituted the depression and non-depression groups, respectively. Based on the questionnaire, the primary outcome was the presence of DED. Additionally, the chi-square test and interaction test were applied to survey the effect of lifestyle and nutritional factors on DED in the depression and non-depression groups.
Results: There were 822 (21.90%) and 958 (12.76%) DED patients in the depression and non-depression groups, respectively, and the incidence of DED was significantly higher in the depression group ( p  < 0.001). In terms of lifestyle and nutritional factors in the depression population, a higher rate of chronic pain and a sedentary lifestyle were observed than in the patients with depression without DED (both p  < 0.05). According to the interaction test, the chronic pain ( p  = 0.0227) and sedentary lifestyle ( p  = 0.0002) were significant risk factors for DED presence in the depression group than in the non-depression group, while the persistent coffee consumption ( p  = 0.0005) and tea consumption ( p  = 0.0003) were significant protective factors for the DED exclusively for the depression group and not for the non-depression group.
Conclusion: The depression population could be significantly benefited from physical activity, coffee intake and tea intake regarding DED development compared to the general population.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2024 Lee, Yang, Lian, Chang, Jhan and Chang.)
Databáze: MEDLINE