A systematic review of the outcomes of partial ulnar collateral ligament tears of the elbow in athletes treated non-operatively with platelet-rich plasma injection.

Autor: Ifarraguerri AM; Sports Medicine Center, OrthoCarolina, Charlotte, NC, USA.; OrthoCarolina Research Institute, Charlotte, NC, USA.; Musculoskeletal Institute, Atrium Health, Charlotte, NC, USA., Berk AN; Sports Medicine Center, OrthoCarolina, Charlotte, NC, USA.; OrthoCarolina Research Institute, Charlotte, NC, USA.; Musculoskeletal Institute, Atrium Health, Charlotte, NC, USA., Rao AJ; University of Minnesota - Department of Orthopedic Surgery, University of Minnesota Physicians, Minneapolis, MN, USA., Trofa DP; New York Presbyterian, Department of Orthopaedics, Columbia University Medical Center, New York, NY, USA., Ahmad CS; New York Presbyterian, Department of Orthopaedics, Columbia University Medical Center, New York, NY, USA., Martin A; Musculoskeletal Institute, Atrium Health, Charlotte, NC, USA., Fleischli JE; Sports Medicine Center, OrthoCarolina, Charlotte, NC, USA.; OrthoCarolina Research Institute, Charlotte, NC, USA.; Musculoskeletal Institute, Atrium Health, Charlotte, NC, USA., Saltzman BM; Sports Medicine Center, OrthoCarolina, Charlotte, NC, USA.; OrthoCarolina Research Institute, Charlotte, NC, USA.; Musculoskeletal Institute, Atrium Health, Charlotte, NC, USA.
Jazyk: angličtina
Zdroj: Shoulder & elbow [Shoulder Elbow] 2024 Jul; Vol. 16 (4), pp. 413-428. Date of Electronic Publication: 2024 Mar 05.
DOI: 10.1177/17585732241235631
Abstrakt: Background: This study aimed to analyze the effects of platelet-rich plasma (PRP) for partial ulnar collateral ligament (UCL) tears in athletes and predicted positive outcomes.
Methods: The researchers systematically reviewed the PubMed, Cochrane CENTRAL, MEDLINE, Scopus, and Google Scholar databases to identify studies with clinical outcomes of PRP for partial UCL tears. They excluded studies that did not stratify data by tear type or included surgical management.
Results: Five studies with 156 patients were included. The timing, amount, platelet concentration, type, and number of PRP injections were highly variable among the studies. However, 75% (n = 97/127) of athletes returned to sport (RTS) at a weighted average of 82.1 days (37-84) after PRP injection. One study showed significant improvements in patient-reported outcomes. Two studies showed positive outcomes in the modified Conway scale, complete reconstitution of the UCL in 87% of patients on MRI, and significant improvement in the humeral-ulnar joint space after PRP injection via ultrasound. The Coleman methodology score (CMS) averaged 48/100, indicating an overall poor quality of evidence.
Conclusion: This review demonstrates favorable RTS, clinical, and radiographic outcomes in patients receiving PRP for partial UCL tears, but the literature remains heterogeneous and of low quality.
Level of Evidence: III.
Competing Interests: Author BMS receives research support from Arthrex, Inc. and publishing royalties, financial, or material support from Nova Science Publishers. JEF received researched support from both Arthrex and Smith & Nephew. C.S.A. received royalties from both Arthrex and Lead Player, has stock or stock options with At Peak, received research support from the MLB, and received research support from Stryker.
(© The Author(s) 2024.)
Databáze: MEDLINE