Initiation of Intermittently Scanned Continuous Glucose Monitoring Is Associated With Reduced Hospitalization for Acute Diabetes Events and Cardiovascular Complications in Adults With Type 1 Diabetes.

Autor:	Eeg-Olofsson K; Sahlgrenska University Hospital and Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden.; Centre of Registers, Västra Götaland Region, Gothenburg, Sweden., Nathanson D; Karolinska University Hospital and Medical Unit Endocrinology and Department of Medicine, Karolinska University Hospital Huddinge, Karolinska Institute, Stockholm, Sweden., Spelman T; Synergus RWE AB, Åkersberga, Sweden., Kyhlstedt M; Synergus RWE AB, Åkersberga, Sweden., Bülow E; Centre of Registers, Västra Götaland Region, Gothenburg, Sweden., Levrat-Guillen F; Abbott Laboratories Ltd., Maidenhead, U.K., Bolinder J; Karolinska University Hospital and Medical Unit Endocrinology and Department of Medicine, Karolinska University Hospital Huddinge, Karolinska Institute, Stockholm, Sweden.
Jazyk:	angličtina
Zdroj:	Diabetes care [Diabetes Care] 2024 Dec 01; Vol. 47 (12), pp. 2164-2171.
DOI:	10.2337/dc24-0690
Abstrakt:	Objective: We assessed the impact of intermittently scanned continuous glucose monitoring (isCGM) compared with blood glucose monitoring (BGM) on rates of hospitalization for metabolic and vascular complications of diabetes and on HbA1c levels for adults with type 1 diabetes. Research Design and Methods: This retrospective study using data from the Swedish National Diabetes Register and the Swedish National Patient Register comprised adults with type 1 diabetes and an isCGM initiation date after 1 June 2017 and matched control individuals using BGM. Hospital admission rates were calculated per 100 person-years of follow-up. Results: We identified 11,822 adults with type 1 diabetes and an isCGM index date after 1 June 2017 and HbA1c baseline values 3-8 months prior to the index date. Compared with 3,007 BGM users, isCGM users had a significantly lower relative risk of hospitalization for hypoglycemia (0.32; 95% CI 0.14, 0.74), diabetic ketoacidosis (0.55; 0.35, 0.87), stroke (0.48; 0.37, 0.64), acute myocardial infarction (0.64; 0.46, 0.91), atrial fibrillation (0.59; 0.38, 0.94), heart failure (0.25; 0.16, 0.39), peripheral vascular disease (0.21; 0.07, 0.62), kidney disease (0.48; 0.35, 0.66), or hospitalization for any reason (0.32; 0.29, 0.35). Compared with BGM users, change in mean HbA1c for isCGM users was -0.30% (-3.3 mmol/mol) at 6 months and -0.24% (-2.6 mmol/mol) at 24 months (both P < 0.001). Conclusions: This study shows that adults with type 1 diabetes in Sweden who initiate isCGM have significantly reduced hospitalization rates for acute diabetes events, kidney disease, and cardiovascular complications, along with improved glucose control, compared with BGM users. (© 2024 by the American Diabetes Association.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu