Non-contrast-enhanced MR-angiography of Extracranial Arteries in Acute Ischemic Stroke at 1.5 Tesla Using Relaxation-Enhanced Angiography Without Contrast and Triggering (REACT).

Autor: Janssen JP; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany. jan.janssen@uk-koeln.de., Rose S; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany., Kaya K; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany., Terzis R; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany., Hahnfeldt R; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany., Gertz RJ; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany., Goertz L; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany., Iuga AI; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany., Grunz JP; University Hospital Wuerzburg, Institute for Diagnostic and Interventional Radiology, Wuerzburg, Germany.; University of Wisconsin-Madison, Madison, WI, USA., Kabbasch C; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany., Rauen P; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany., Persigehl T; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany., Weiss K; Philips GmbH, Hamburg, Germany., Borggrefe J; Department of Radiology, Neuroradiology and Nuclear Medicine, Johannes Wesling University Hospital, Ruhr University Bochum, Bochum, Germany., Pennig L; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany., Gietzen C; Faculty of Medicine and University Hospital Cologne, University of Cologne, Institute for Diagnostic and Interventional Radiology, Kerpener Straße 62, 50937, Cologne, Germany.
Jazyk: angličtina
Zdroj: Clinical neuroradiology [Clin Neuroradiol] 2024 Sep 24. Date of Electronic Publication: 2024 Sep 24.
DOI: 10.1007/s00062-024-01458-4
Abstrakt: Purpose: To evaluate a novel flow-independent sequence (Relaxation-Enhanced Angiography without Contrast and Triggering (REACT)) for imaging of the extracranial arteries in acute ischemic stroke (AIS) at 1.5 T.
Methods: This retrospective single-center study included 47 AIS patients who received REACT (scan time: 3:01 min) and contrast-enhanced MRA (CE-MRA) of the extracranial arteries at 1.5 T in clinical routine. Two radiologists assessed scans for proximal internal carotid artery (ICA) stenosis, stated their diagnostic confidence and rated the image quality of cervical arteries, impact of artifacts and image noise. Apparent signal- and contrast-to-noise ratios (aSNR/aCNR) were measured for the common carotid artery and ICA.
Results: REACT achieved a sensitivity of 95.0% and a specificity of 97.3% for ICA stenoses in high agreement with CE-MRA (κ = 0.83) with equal diagnostic confidence (p = 0.22). Image quality was rated higher for CE-MRA at the aortic arch (p = 0.002) and vertebral arteries (p < 0.001), whereas REACT provided superior results for the extracranial ICA (p = 0.008). Both sequences were only slightly affected by artifacts (p = 0.60), while image noise was more pronounced in CE-MRA (p < 0.001) in line with higher aSNR (p < 0.001) and aCNR (p < 0.001) values in REACT for all vessels.
Conclusion: Given its good diagnostic performance while yielding comparable image quality and scan time to CE-MRA, REACT may be suitable for the imaging of the extracranial arteries in acute ischemic stroke at 1.5 T.
(© 2024. The Author(s).)
Databáze: MEDLINE
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