Understanding p -values and significance.
| Autor: | Altman N; Department of Statistics, The Pennsylvania State University, State College, PA, USA., Krzywinski M; Canada's Michael Smith Genome Sciences Centre, Vancouver, British Columbia, Canada. |
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| Jazyk: | angličtina |
| Zdroj: | Laboratory animals [Lab Anim] 2024 Oct; Vol. 58 (5), pp. 443-447. Date of Electronic Publication: 2024 Sep 24. |
| DOI: | 10.1177/00236772241247106 |
| Abstrakt: | P- values combined with estimates of effect size are used to assess the importance of experimental results. However, their interpretation can be invalidated by selection bias when testing multiple hypotheses, fitting multiple models or even informally selecting results that seem interesting after observing the data. We offer an introduction to principled uses of p -values (targeted at the non-specialist) and identify questionable practices to be avoided. Competing Interests: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
| Databáze: | MEDLINE |
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