Schmidt´s syndrome found by tan: a case report.
| Autor: | Venade G; Internal Medicine Department, Centro Hospitalar Tondela Viseu, Viseu, Portugal., Almeida C; Internal Medicine Department, Centro Hospitalar Tondela Viseu, Viseu, Portugal., Oliveira N; Internal Medicine Department, Centro Hospitalar Tondela Viseu, Viseu, Portugal., Matos LC; Internal Medicine Department, Centro Hospitalar Tondela Viseu, Viseu, Portugal. |
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| Jazyk: | angličtina |
| Zdroj: | The Pan African medical journal [Pan Afr Med J] 2024 Jun 10; Vol. 48, pp. 53. Date of Electronic Publication: 2024 Jun 10 (Print Publication: 2024). |
| DOI: | 10.11604/pamj.2024.48.53.35130 |
| Abstrakt: | Addison´s disease can form part of type 2 autoimmune polyglandular syndrome. The article reports the case of a 41-year-old female patient with hypothyroidism and vitiligo, who came to the emergency department complaining of asthenia that had worsened in recent months, as well as anorexia, nausea, and weight loss (6 kg in a year). Cutaneous hyperpigmentation was the main finding on physical examination, together with vitiligo lesions on the face, hands, and armpits. Further study revealed a low serum cortisol level, normal urine-free cortisol, and an elevated adrenocorticotropic hormone (ACTH). Antiperoxidase antibodies and 17-alpha-hidroxylase antibodies were both positive. Treatment was started with prednisolone and fludrocortisone, and a good clinical response was obtained. This case report aims to draw attention to the high level of clinical suspicion required to diagnose Addison´s disease and the need to screen actively for other potentially associated autoimmune diseases that may be associated. Competing Interests: The authors declare no competing interests. (Copyright: Gabriela Venade et al.) |
| Databáze: | MEDLINE |
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