Cupin-domain containing protein is not essential for the alkyl salicylaldehyde formation in Aspergillus ustus .
| Autor: | Peter M; Institut für Pharmazeutische Biologie und Biotechnologie, Fachbereich Pharmazie, Philipps-Universität Marburg, Marburg 35037, Germany. shuming.li@pharmazie.uni-marburg.de., Li SM; Institut für Pharmazeutische Biologie und Biotechnologie, Fachbereich Pharmazie, Philipps-Universität Marburg, Marburg 35037, Germany. shuming.li@pharmazie.uni-marburg.de. |
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| Jazyk: | angličtina |
| Zdroj: | Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Oct 08; Vol. 60 (81), pp. 11556-11559. Date of Electronic Publication: 2024 Oct 08. |
| DOI: | 10.1039/d4cc04227a |
| Abstrakt: | Previous studies demonstrated the requirement of four enzymes including a cupin-domain containing protein for the formation of alkyl salicylaldehydes and derivatives. Heterologous expression of three biosynthetic genes from Aspergillus ustus resulted in the formation of such compounds in high-yields without involvement of a cupin analogue. |
| Databáze: | MEDLINE |
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