Working Status in Patients With Untreated Unruptured Intracranial Aneurysms: A Descriptive Longitudinal Study.

Autor: Majewska P; Department of Neurosurgery, St. Olav's University Hospital, Trondheim, Norway.; Department of Neuromedicine and Movement Science, NTNU, Trondheim, Norway., Sandvei MS; Department of Clinical and Molecular Medicine, NTNU, Trondheim, Norway.; The Cancer Clinic, St. Olav's University Hospital, Trondheim, Norway., Gulati S; Department of Neurosurgery, St. Olav's University Hospital, Trondheim, Norway.; Department of Neuromedicine and Movement Science, NTNU, Trondheim, Norway., Müller TB; Department of Neurosurgery, St. Olav's University Hospital, Trondheim, Norway., Hara KW; Department of Public Health and Nursing, NTNU, Trondheim, Norway.; The Norwegian Labour and Welfare Administration for Trøndelag, Trondheim, Norway., Romundstad PR; Department of Clinical and Molecular Medicine, NTNU, Trondheim, Norway., Solheim O; Department of Neurosurgery, St. Olav's University Hospital, Trondheim, Norway.; Department of Neuromedicine and Movement Science, NTNU, Trondheim, Norway.
Jazyk: angličtina
Zdroj: Neurosurgery [Neurosurgery] 2024 Sep 23. Date of Electronic Publication: 2024 Sep 23.
DOI: 10.1227/neu.0000000000003185
Abstrakt: Background and Objectives: Many patients with unruptured intracranial aneurysms (UIAs) remain untreated if the risk of treatment exceeds the estimated risk of aneurysm rupture, potentially leading to diagnosis-related stress and anxiety. Working status may serve as a marker for the total level of function including mental health and psychological burden of the condition. The aim of the study was to assess the working status before and after a diagnosis of an untreated UIA.
Methods: This was a retrospective nationwide registry-based descriptive longitudinal study. It included all working-age patients diagnosed with an UIA in Norway between 2008 and 2018 and 1:1 age-matched and sex-matched controls without a diagnosis of an intracranial aneurysm that were randomly selected from the Norwegian population. The history of sickness absence in the period of 1 year before and after diagnosis was retrieved from The Norwegian Labour and Welfare Administration records and compared between the groups.
Results: In total, 2141 patients and 2141 controls were included in the study. Proportion of working patients decreased from 62.1% (95% CI 60.0%-64.1%) 1 year before the diagnosis to 51.3% (95% CI 49.1%-53.4%) 1 year after the diagnosis (P < .001). In comparison, the proportion of working controls decreased from 77.9% (95% CI 76.1%-79.6%) 1 year before day 0 to 73.4% (95% CI 71.5%-75.2%) 1 year after day 0 (P = .001). The odds of working were 86.7% lower among the patients than among the controls (odds ratio 0.133, 95% CI 0.091-0.194; P < .001) when controlled for the baseline working status. The older the individuals, the less likely they were to work (odds ratio 0.908, 95% CI 0.889-0.926; P < .001).
Conclusion: The work participation of patients diagnosed with UIA is low prediagnosis compared with the general population and decreases significantly postdiagnosis.
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Databáze: MEDLINE