Exploring the functionality of fluorescent liposomes in cancer: diagnosis and therapy.
| Autor: | Prajapati BG; Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva 384012, India.; Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand., Sharma JB; MM College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala 133207, India., Pareek A; Department of Pharmacy, Banasthali Vidyapith, Banasthali 304022, India., Garg R; Asian College of Pharmacy, Udaipur 313001, India., Saini PK; Department of Pharmaceutics, Sri Balaji College of Pharmacy, Jaipur, Rajasthan 302026, India., Kapoor DU; Dr. Dayaram Patel Pharmacy College, Bardoli, Gujarat 394601, India. |
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| Jazyk: | angličtina |
| Zdroj: | Zeitschrift fur Naturforschung. C, Journal of biosciences [Z Naturforsch C J Biosci] 2024 Sep 24. Date of Electronic Publication: 2024 Sep 24. |
| DOI: | 10.1515/znc-2024-0144 |
| Abstrakt: | Fluorescent liposomes are pivotal in cancer research, serving as adaptable vehicles for imaging and therapeutics. These small lipid vesicles, capable of encapsulating fluorescent dyes, offer precise visualization and monitoring of their targeted delivery to cancer cells. This review delves into the critical role fluorescent liposomes play in enhancing both cancer diagnosis and treatment. It provides an in-depth analysis of their structural features, fluorescent labeling techniques, targeting strategies, and the challenges and opportunities they present. In the domain of cancer diagnosis, the article sheds light on various imaging modalities enabled by fluorescent liposomes, including fluorescence imaging and multimodal techniques. Emphasis is placed on early detection strategies, exhibiting the utility of targeted contrast agents and biomarker recognition for enhanced diagnostic precision. Moving on to cancer treatment, the review discusses the sophisticated drug delivery mechanisms facilitated by fluorescent liposomes, focusing on chemotherapy and photodynamic therapy. Moreover, the exploration extends to targeted therapy, explaining the applications of fluorescent liposomes in gene delivery and RNA interference. In a nutshell, his article comprehensively explores the multifaceted impact of fluorescent liposomes on advancing cancer diagnosis and treatment, combining existing knowledge with emerging trends. (© 2024 Walter de Gruyter GmbH, Berlin/Boston.) |
| Databáze: | MEDLINE |
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