| Autor: |
Imani K; Department of Organic Chemistry, Shahid Beheshti University, Tehran 1983969411, Iran., Shirazi H; Department of Organic Chemistry, Shahid Beheshti University, Tehran 1983969411, Iran., Golchin G; Department of Organic Chemistry, Shahid Beheshti University, Tehran 1983969411, Iran., Bazgir A; Department of Organic Chemistry, Shahid Beheshti University, Tehran 1983969411, Iran. |
| Abstrakt: |
A new, mild, and diastereoselective method has been developed for the synthesis of β-pyridone-α,β-unsaturated oxindoles by the reaction of isatins and 2-chloropyridinium salts in EtOH at room temperature for 5 min. This method operates under mild reaction conditions, providing the product with a good yield and diastereoselectivity, and it exhibits excellent tolerance toward various functional groups. The predominant isomer is the Z isomer, which can convert to the E isomer in the presence of NaN 3 . |
