The importance of timing of socioeconomic disadvantage throughout development for depressive symptoms and brain structure.

Autor:	Ferschmann L; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway. Electronic address: lia.ferschmann@psykologi.uio.no., Grydeland H; Center for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo, Norway., MacSweeney N; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway., Beck D; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway., Bos MGN; Leiden Institute for Brain and Cognition, Leiden University, Leiden, the Netherlands; Institute of Psychology, Leiden University, Leiden, the Netherlands, Leiden University, Leiden, the Netherlands., Norbom LB; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway., Aksnes ER; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway., Bekkhus M; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway., Havdahl A; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway; Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway; Nic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway., Crone EA; Erasmus School of Social and Behavioral Sciences, Erasmus University Rotterdam, Rotterdam, the Netherlands., von Soest T; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway., Tamnes CK; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway; Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.
Jazyk:	angličtina
Zdroj:	Developmental cognitive neuroscience [Dev Cogn Neurosci] 2024 Oct; Vol. 69, pp. 101449. Date of Electronic Publication: 2024 Sep 13.
DOI:	10.1016/j.dcn.2024.101449
Abstrakt:	Prior studies have reported associations between socioeconomic disadvantage, brain structure and mental health outcomes, but the timing of these relations is not well understood. Using prospective longitudinal data from the Avon Longitudinal Study of Parents and Children (ALSPAC), this preregistered study examined whether socioeconomic disadvantage related differentially to depressive symptoms (n=3012-3530) and cortical and subcortical structures (n=460-733) in emerging adults, depending on the timing of exposure to socioeconomic disadvantage. Family income in early childhood and own income measured concurrently were both significantly related to depressive symptoms in emerging adulthood. Similar results were observed for perceived financial strain. In contrast, only family income in early childhood was associated with brain structure in emerging adulthood, with positive associations with intracranial volume and total and regional cortical surface area. The findings suggest that both objective and subjective aspects of one's financial standing throughout development relate to depressive symptoms in adulthood, but that specifically early life family income is related to brain structural features in emerging adulthood. This suggests that associations between socioeconomic disadvantage and brain structure originate early in neurodevelopment, highlighting the role of timing of socioeconomic disadvantage. Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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