| Autor: |
Kostyleva DN; Endocrinology Research Centre., Khandaeva PM; Endocrinology Research Centre., Lapshina AM; Endocrinology Research Centre., Przhialkovskaya EG; Endocrinology Research Centre., Belaya ZE; Endocrinology Research Centre., Grigoriev АY; Endocrinology Research Centre., Mel'nichenko GA; Endocrinology Research Centre. |
| Jazyk: |
ruština |
| Zdroj: |
Problemy endokrinologii [Probl Endokrinol (Mosk)] 2024 Sep 15; Vol. 70 (4), pp. 24-31. Date of Electronic Publication: 2024 Sep 15. |
| DOI: |
10.14341/probl13349 |
| Abstrakt: |
According to numerous studies, the most common pituitary tumors are prolactinomas, reaching 60% of all clinically significant adenomas, the next in order are non-functional pituitary adenomas, somatotropinomas, corticotropinomas and thyrotropinomas. Plurigormonal tumors occur in less than 1% of all pituitary adenomas. The most common form of mixed secretion adenoma in this patient population, derived from the Pit-1 cell line, produces various combinations of hormones: growth hormone (GH), prolactin (PRL), thyroid-stimulating hormone (TSH). This article presents a patient with a plurihormonal two-component pituitary macroadenoma with a rare and exceptional combination of secreted hormones - GH / adrenocorticotropic hormone (ACTH) / TSH / follicle-stimulating hormone (FSH) / luteinizing hormone (LH) with minimal nonspecific clinical manifestations such as diabetes mellitus and poorly controlled arterial hypertension. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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