Subtle Presentation of Two Rare Gynecological Cancers in a Single Patient: A Case Report.

Autor:	Estevez E; Obstetrics and Gynecology, St. George's University School of Medicine, St. George, GRD., Friedman F; Obstetrics and Gynecology, Icahn School of Medicine at Mount Sinai, Elmhurst Hospital Center, Queens, USA., Huang T; Pathology, Icahn School of Medicine at Mount Sinai, Elmhurst Hospital Center, Queens, USA., Morgenstern N; Pathology, Icahn School of Medicine at Mount Sinai, Elmhurst Hospital Center, Queens, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Aug 19; Vol. 16 (8), pp. e67239. Date of Electronic Publication: 2024 Aug 19 (Print Publication: 2024).
DOI:	10.7759/cureus.67239
Abstrakt:	Yolk sac tumors (YSTs) are rare germ-cell malignancies that usually develop in the gonads. Similarly, gastric-type adenocarcinoma of the endocervix (GAS) is a rare kind of gynecological cancer that has piqued interest due to its distinctive clinical and pathological features. These two malignancies in a single patient present a unique and challenging scenario. Here, we present the case of a 33-year-old female who presented with postcoital bleeding and was diagnosed with atypical glandular proliferation consistent with GAS. Interestingly, this patient had a history of a YST treated with left salpingo-oophorectomy and chemoradiation in the Philippines five years prior. A follow-up ultrasound report in the Philippines five months after treatment showed no evidence of residual disease. This case report aims to understand the predisposing factors of these neoplasms and asks if there is a link between them, which is necessary for tailoring surveillance, appropriate therapeutic approaches, and improving patient outcomes. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Estevez et al.)
Databáze:	MEDLINE
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