Localized retroperitoneal mass suspected malignancy: A rare case of unicentric Castleman's disease.

Autor: Alhariry ES; Pathology Department Shefaa Al Orman Hospital Luxor Egypt., Hasan A; Faculty of Medicine Al-Azhar University Cairo Egypt., Abdelghany A; Faculty of Medicine Al-Azhar University Cairo Egypt.; Faculty of Medicine University of Granada Granada Spain., Nafie K; Pathology and Laboratory Medicine Ministry of Health Khartoum Sudan.
Jazyk: angličtina
Zdroj: Clinical case reports [Clin Case Rep] 2024 Sep 18; Vol. 12 (9), pp. e9451. Date of Electronic Publication: 2024 Sep 18 (Print Publication: 2024).
DOI: 10.1002/ccr3.9451
Abstrakt: Key Clinical Message: Castleman's Disease should be considered in the differential diagnosis of retroperitoneal masses, especially in equivocal cases. Clinician should not presume all cases of retroperitoneal masses as a malignancy.
Abstract: Castleman's Disease is a heterogeneous group of lymphoproliferative disorders, that can develop in lymph nodes or in extranodal sites. It has three distinct histological subtypes; hyaline vascular, plasma cell or mixed. It can be unicentric or multicentric, and sometimes oligocentric or regional. In this article, we report a case of a 30-year-old male who presented with a palpable left lumbar mass, clinically suspected as sarcoma vs GIST, which was surgically excised and pathologically examined revealing a rare condition of intra-abdominal unicentric Castleman's Disease with good prognosis. Castleman's Disease should be considered in the differential diagnosis of retroperitoneal masses, especially in equivocal cases.
Competing Interests: All authors declare no any COI.
(© 2024 The Author(s). Clinical Case Reports published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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