Psychosocial outcomes with the Omnipod® 5 Automated Insulin Delivery System in caregivers of very young children with type 1 diabetes.

Autor: MacLeish SA; University Hospitals Cleveland Medical Center, Rainbow Babies and Children's Hospital, Cleveland, Ohio, USA., Hood KK; Department of Pediatrics, Psychiatry, & Behavioral Sciences, Stanford University School of Medicine, Stanford Diabetes Research Center, Stanford, California, USA., Polonsky WH; Behavioral Diabetes Institute, San Diego, California, USA.; University of California San Diego, San Diego, California, USA., Wood JR; University Hospitals Cleveland Medical Center, Rainbow Babies and Children's Hospital, Cleveland, Ohio, USA., Bode BW; Atlanta Diabetes Associates, Atlanta, Georgia, USA., Forlenza GP; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Laffel LM; Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA., Buckingham BA; Division of Pediatric Endocrinology, Department of Pediatrics, Stanford University, Stanford, California, USA., Criego AB; International Diabetes Center/HealthPartners Institute, Park Nicollet Clinic Pediatric Endocrinology, Minneapolis, Minnesota, USA., Schoelwer MJ; Center for Diabetes Technology, University of Virginia, Charlottesville, Virginia, USA., DeSalvo DJ; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA., Sherr JL; Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA., Hansen DW; Department of Pediatrics, SUNY Upstate Medical University, Syracuse, New York, USA., Conroy LR; Insulet Corporation, Acton, Massachusetts, USA., Huyett LM; Insulet Corporation, Acton, Massachusetts, USA., Vienneau TE; Insulet Corporation, Acton, Massachusetts, USA., Ly TT; Insulet Corporation, Acton, Massachusetts, USA.
Jazyk: angličtina
Zdroj: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Dec; Vol. 26 (12), pp. 5569-5579. Date of Electronic Publication: 2024 Sep 20.
DOI: 10.1111/dom.15906
Abstrakt: Aim: Automated insulin delivery (AID) systems have demonstrated improved glycaemic outcomes in people with type 1 diabetes (T1D), yet limited data exist on these systems in very young children and their impact on caregivers. We evaluated psychosocial outcomes following use of the tubeless Omnipod® 5 AID System in caregivers of very young children.
Materials and Methods: This 3-month single-arm, multicentre, pivotal clinical trial enrolled 80 children aged 2.0-5.9 years with T1D to use the Omnipod 5 AID System. Caregivers completed questionnaires assessing psychosocial outcomes-diabetes distress (Problem Areas in Diabetes), hypoglycaemia confidence (Hypoglycemia Confidence Scale), well-being (World Health Organization 5 Well-Being Index), sleep quality (Pittsburgh Sleep Quality Index), insulin delivery satisfaction (Insulin Delivery Satisfaction Survey) and system usability (System Usability Scale) at baseline with standard therapy and after 3 months of AID use.
Results: Following 3 months of Omnipod 5 use, caregivers experienced significant improvements across all measures, including diabetes-related psychosocial outcomes (Problem Areas in Diabetes; p < 0.0001, Hypoglycemia Confidence Scale; p < 0.01), well-being (World Health Organization 5 Well-Being Index; p < 0.0001) and perceived system usability (System Usability Scale; p < 0.0001). Significant improvements were seen in the Pittsburgh Sleep Quality Index total score and the overall sleep quality, sleep duration and efficiency subscales (all p < 0.05). Insulin Delivery Satisfaction Survey scores improved on all subscales (greater satisfaction, reduced burden and reduced inconvenience; all p < 0.0001).
Conclusions: Caregivers face unique challenges when managing T1D in very young children. While glycaemic metrics have unquestioned importance, these results evaluating psychosocial outcomes reveal additional meaningful benefits and suggest that the Omnipod 5 AID System alleviates some of the burdens caregivers face with diabetes management.
(© 2024 Insulet Corporation and The Author(s). Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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