Effectiveness of an affect-adjusted, supervised, multimodal, online and home-based exercise group protocol for major depression: A randomized controlled trial.

Autor: Tavares VDO; Laboratory of Hormone Measurement, Department of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal, Brazil; Graduate Program in Psychobiology, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, Brazil; Department of Community Health Sciences, University of Calgary, Canada; Faculty of Nursing, University of Calgary, Calgary, AB, Canada., Schuch FB; Department of Sports Methods and Techniques, Federal University of Santa Maria, Santa Maria, Brazil; Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Institute of Health Sciences, Universidad Autónoma de Chile, Providencia, Chile., de Sousa GM; Laboratory of Hormone Measurement, Department of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal, Brazil; Graduate Program in Psychobiology, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, Brazil., Hallgren M; Department of Global Public Health, Karolinska Institute, Stockholm, Sweden., Oliveira Neto L; Research Group in Biomechanics (GEBIO), Department of Physical Education, Federal University of Rio Grande do Norte, Natal-RN, Brazil., Cabral DAR; Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, USA., Nóbrega de Almeida R; Laboratory of Hormone Measurement, Department of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal, Brazil., Barbosa DC; Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, Natal, Brazil., de Almeida VRN; Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, Natal, Brazil., Tinoco H; Laboratory of Hormone Measurement, Department of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal, Brazil., Lira RA; Laboratory of Hormone Measurement, Department of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal, Brazil., Hallak JE; Neurosciences and Behavior Department, Ribeirao Preto Medical School, University of Sao Paulo, Brazil; National Institute of Science and Technology for Translational Medicine - INCT TM - CNPq/FAPESP/CAPES, Brazil., Arcoverde E; Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, Natal, Brazil; National Institute of Science and Technology for Translational Medicine - INCT TM - CNPq/FAPESP/CAPES, Brazil., Cuthbert C; Faculty of Nursing, University of Calgary, Calgary, AB, Canada; Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Patten S; Department of Community Health Sciences, University of Calgary, Canada., Galvão-Coelho NL; Laboratory of Hormone Measurement, Department of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal, Brazil; Graduate Program in Psychobiology, Center for Biosciences, Federal University of Rio Grande do Norte, Natal, Brazil; National Institute of Science and Technology for Translational Medicine - INCT TM - CNPq/FAPESP/CAPES, Brazil; NICM Health Research Institute, Western Sydney University, Westmead, New South Wales, Australia. Electronic address: nicole.galvao@ufrn.br.
Jazyk: angličtina
Zdroj: Psychology of sport and exercise [Psychol Sport Exerc] 2025 Jan; Vol. 76, pp. 102729. Date of Electronic Publication: 2024 Sep 18.
DOI: 10.1016/j.psychsport.2024.102729
Abstrakt: This randomized controlled trial investigated the effectiveness of an affect-adjusted, supervised, multimodal, online, and home-based exercise group protocol as an adjunct therapy to antidepressants on depressive symptoms, cardiorespiratory fitness, and side effects related to antidepressants in adults with major depression (MDD, diagnosed by a clinician). Depressive symptom scales were administered by a psychiatrist and self-reported. A health-related measure (i.e., cardiorespiratory fitness), was also administered. The exercise intervention was adjusted by perceived effort and affect (pleasure and enjoyment) toward exercise and lasted 12 weeks. In total, 59 adults with MDD were divided into two groups: the exercise-group (EG; exercise + pharmacotherapy) with 26-patients (76.9 % females, mean age 28.5 years) and the control-group (CG, pharmacotherapy) with 33-patients (78.7 % females, mean age 25.6 years). The EG had a lower dropout rate (15.3 %) than CG and an increase in cardiorespiratory fitness (CRF), which was not observed in the CG. Both groups showed a decrease in self-reported depressive symptoms. However, the EG had significantly lower depressive symptom scores at t1 and t2. The EG also had higher remission rates (t1, EG: = 42.3 % and CG = 27.2 %) and remission rates (t2, EG: = 72.7 % and CG = 48.1 %) than CG, which were maintained during the four month follow-up. Side effects from anti-depressant medication were larger in the EG compared to CG. Complementing usual care for MDD with exercise resulted in better clinical outcomes and supports the use of this type of exercise protocol in the clinical management of depression.
Competing Interests: Declaration of competing interest The Authors declares that there is no conflict of interest.
(Copyright © 2024. Published by Elsevier Ltd.)
Databáze: MEDLINE
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